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pd_meltingpoint:41678oC
Appearance:powder
Purity:99%
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Biochem/physiol Actions |
XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is acted upon by dehydrogenases present in metabolically active cells. This produces water soluble formazan, which is a highly colored product. Thus, it offers an advantage in colorimetric proliferation assays, as opposed to MTT, as the product is already soluble and no formazan crystals are formed. |
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General Description |
XTT (sodium 3′-[1-[(phenylamino)-carbony]-3,4-tetrazolium]-bis(4-methoxy-6-nitro)benzene-sulfonic acid hydrate) is a tetrazolium salt, which forms water-soluble formazan on bioreduction. |
InChI:InChI=1/C22H19N7O13S2.2Na.H2O/c1-41-18-8-16(28(31)32)20(43(35,36)37)10-14(18)26-12-25(22(30)23-13-6-4-3-5-7-13)24-27(26)15-11-21(44(38,39)40)17(29(33)34)9-19(15)42-2;;;/h3-12H,1-2H3,(H,23,30)(H,35,36,37)(H,38,39,40);;;1H2/q+2;2*+1;/p-2
A new tetrazolium salt, XTT, has been sy...
3,3'-<<3-(phenylamino)carbonyl>-1,5-formazandiyl>bis(4-methoxy-6-nitro)benzenesulfonic acid disodium salt
sodium 3,3'-<1-<(phenylamino)carbonyl>-3,4-tetrazolium>-bis(4-methoxy-6-nitro)benzenesulfonic acid
| Conditions | Yield |
|---|---|
|
With
sodium hypochlorite;
In
water;
at 18 ℃;
for 0.5h;
|
27% |
sodium 3,3'-<1-<(phenylamino)carbonyl>-3,4-tetrazolium>-bis(4-methoxy-6-nitro)benzenesulfonic acid
3,3'-<<3-(phenylamino)carbonyl>-1,5-formazandiyl>bis(4-methoxy-6-nitro)benzenesulfonic acid disodium salt
| Conditions | Yield |
|---|---|
|
With
sodium hydrogencarbonate; ascorbic acid;
In
water;
for 1.5h;
Ambient temperature;
|
400 mg |
3,3'-<<3-(phenylamino)carbonyl>-1,5-formazandiyl>bis(4-methoxy-6-nitro)benzenesulfonic acid disodium salt
3,3'-<<3-(phenylamino)carbonyl>-1,5-formazandiyl>bis(4-methoxy-6-nitro)benzenesulfonic acid disodium salt
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