Your Location：Home >Products >Inhibitor >133845-63-3
Purity:99%
An improved synthetic sequence for the s...
(5-(benzyloxy)-1H-indol-2-yl)methanol
N-((5-(benzyloxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: 93 percent / MnO2, NaCl / tetrahydrofuran / 90 h / Ambient temperature
2: 1.) molecular sieves 4A, 2.) NaBH4 / 1.) THF, RT, 24 h, 2.) MeOH, RT, 30 min
With
manganese(IV) oxide; sodium tetrahydroborate; 4 A molecular sieve; sodium chloride;
In
tetrahydrofuran;
|
5-benzyloxy-1H-indole-2-carboxylic acid ethyl ester
N-((5-(benzyloxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 3 steps
1: 93 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
2: 93 percent / MnO2, NaCl / tetrahydrofuran / 90 h / Ambient temperature
3: 1.) molecular sieves 4A, 2.) NaBH4 / 1.) THF, RT, 24 h, 2.) MeOH, RT, 30 min
With
manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; 4 A molecular sieve; sodium chloride;
In
tetrahydrofuran;
|
2-(5-benzyloxyindole)carboxyaldehyde
Propargylamine
(5-(benzyloxy)-1H-indol-2-yl)methanol
5-benzyloxy-1H-indole-2-carboxylic acid ethyl ester
