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pd_meltingpoint:125-128 °C(lit.)
Appearance:Cream powder
Purity:99%
An efficient, commercially viable and sa...
A series of eight 4′-[4-(3-substituted p...
Herein, we report the synthesis and scre...
With the redesign of three chemical step...
A new modular photochemical continuous s...
The invention provides a photocatalytic ...
The invention discloses a preparation me...
The invention discloses a preparation me...
2-Cyano-4'-methylbiphenyl
2-(4,4-dibromomethylphenyl)benzonitrile
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
| Conditions | Yield |
|---|---|
|
With
N-Bromosuccinimide; Azo-bis(2,4-dimethyl-valeronitril);
In
dichloromethane;
at 45 - 50 ℃;
for 2 - 5h;
Industry scale;
|
82% |
|
With
sodium bromate; hydrogen bromide;
In
dichloromethane; water;
at 0 - 20 ℃;
UV-irradiation;
|
80% 10% |
|
With
sodium bromate; azobis(2-cyanobutane); bromine;
In
water; chlorobenzene;
at 70 - 80 ℃;
for 6h;
|
69% |
|
With
N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile);
In
tetrachloromethane; cyclohexane;
at 75 ℃;
for 18h;
|
45% 17% |
|
With
sodium bromate; bromine;
2,2'-azobis(isobutyronitrile);
In
water; chlorobenzene;
at 70 - 85 ℃;
for 5h;
|
63.6 %Chromat. 36.2 %Chromat. |
|
With
sodium bromate; azobis(2-cyanobutane); bromine;
In
water; chlorobenzene;
at 70 - 85 ℃;
for 5h;
|
|
|
With
N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile);
In
dichloromethane;
at 40 - 45 ℃;
for 4 - 5h;
|
|
|
With
N-Bromosuccinimide;
In
acetonitrile;
Overall yield = 164 mg;
Irradiation;
Flow reactor;
|
2-cyano-4-methylbiphenyl
4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile
| Conditions | Yield |
|---|---|
|
With
5,5-dibromohydantoin;
In
dichloromethane;
at 50 ℃;
for 0.5h;
Temperature;
Reagent/catalyst;
Irradiation;
|
94% |
|
With
N-Bromosuccinimide; dibenzoyl peroxide;
In
tetrachloromethane;
at 100 ℃;
for 2h;
|
2-Cyano-4'-methylbiphenyl
2-cyanobenzoic acid
ammonium 2-(aminocarbonyl)benzoate
2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline
methyl 2-
2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imidazole
4-(2-Cyanophenyl)benzaldehyde
2-(2'-Cyano-biphenyl-4-ylmethyl)-3-cyclopropyl-3-oxo-propionic acid ethyl ester
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