What is the Dibenzylamine?

Dibenzylamine is Colorless to light yellow liquid, while it's Molecular Formula is C14H15N. Colorless to light yellow liquid Dibenzylamine is used to prepare rubber accelerator for the vulcanization process and reaction-stoppers. Dibenzylamine type accelerators reduce nitrosamine production in the compounding process. It is also used to produce dibenzyl-nitroso-amine.

What is the CAS number for Dibenzylamine?

The CAS number of Dibenzylamine is 103-49-1.

What is Dibenzylamine (103-49-1) used for?

Dibenzylamine is a colorless to light yellow oily liquid with an ammonia odor. It is soluble in ethanol and ether but insoluble in water. It is an important organic synthesis intermediate.InChI:InChI=1/C14H15N/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2/p+1

What is the Dibenzylamine?

Dibenzylamine is Colorless to light yellow liquid, while it's Molecular Formula is C14H15N. Colorless to light yellow liquid Dibenzylamine is used to prepare rubber accelerator for the vulcanization process and reaction-stoppers. Dibenzylamine type accelerators reduce nitrosamine production in the compounding process. It is also used to produce dibenzyl-nitroso-amine.

What is the CAS number for Dibenzylamine?

The CAS number of Dibenzylamine is 103-49-1.

What is Dibenzylamine (103-49-1) used for?

Dibenzylamine is a colorless to light yellow oily liquid with an ammonia odor. It is soluble in ethanol and ether but insoluble in water. It is an important organic synthesis intermediate.InChI:InChI=1/C14H15N/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2/p+1

Product classification

Contact us

Tel：+86-0533-2185556
Fax：+86-0533-2185556
Phone：+86 15965530500
Website：http://www.shandonghangyu.com/
Email：admin@hangyubiotech.com
Address：Room 2516, Dingcheng Building, Beijing Road, Zhangdian District, Zibo City, Shandong Province

103-49-1

Product Name:Dibenzylamine
Molecular Formula:C₁₄H₁₅N
Molecular Weight:197.28
Appearance:Colorless to light yellow liquid

Inquiry

Product Details

pd_meltingpoint:-26 °C(lit.)

Appearance:Colorless to light yellow liquid

Purity:99%

Manufacturer supply Dibenzylamine 103-49-1 with sufficient stock and high standard

Molecular Formula:C14H15N
Molecular Weight:197.28
Appearance/Colour:Colorless to light yellow liquid
Vapor Pressure:0.00115mmHg at 25°C
Melting Point:-26 °C(lit.)
Refractive Index:n20/D 1.574(lit.)
Boiling Point:300 °C at 760 mmHg
PKA:pK1:8.52(+1) (25°C)
Flash Point:143.3 °C
PSA：12.03000
Density:1.026 g/cm³
LogP:3.36730

Dibenzylamine(Cas 103-49-1) Usage

Preparation	Dibenzylamine is obtained by the reaction of benzyl chloride and liquid ammonia in ethanol.
Synthesis Reference(s)	Tetrahedron Letters, 26, p. 4633, 1985 DOI: 10.1016/S0040-4039(00)98771-9The Journal of Organic Chemistry, 60, p. 5969, 1995 DOI: 10.1021/jo00123a041
Purification Methods	Purify the amine by distillation in a vacuum. It causes burns to the skin. The dihydrochloride has m 265-266o (from MeOH/HCl), and the tetraphenyl boronate has m 129-133o. [Bradley & Maisey J Chem Soc 247 1954, Hall J Phys Chem 60 63 1956, Donetti & Bellora J Org Chem 37 3352 1972, Beilstein 12 IV 2179.]
General Description	Dibenzylamine (DBA) is a secondary amine used as a reactant in various synthetic processes, including the synthesis of 2-substituted 2H-chromenes, where it facilitates the reaction between potassium vinyltrifluoroborates and salicylaldehyde. It also serves as a substrate in oxidative N-dealkylation studies involving cupric hydroperoxide intermediates, leading to benzaldehyde formation. Additionally, dibenzylamine-derived compounds are employed in enantioselective reactions, such as the catalytic α-aminomethylation of aldehydes and dynamic kinetic resolution of α-halo acids, yielding β-dibenzylamino alcohols and other valuable intermediates for pharmaceuticals. Its versatility in organic synthesis highlights its role as a key reagent in producing heterocyclic compounds and chiral building blocks.
Application	Dibenzylamine is an important organic synthesis intermediate, mainly used to produce efficient and non-toxic vulcanization accelerators tetrabenzylthiuramdisulfide (TBZTD) and zinc dibenzyldithiocarbamate (ZBEC). Synthesize penicillin and curing agent for rubber and plastic curing, and can be used in the detection of cobalt, cyanate, and iron.

InChI:InChI=1/C14H15N/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2/p+1

103-49-1 Relevant articles

Reductive amination of aldehydes and ketones with 2-(Tributylamino)- ethoxyborohydride

Mohanazadeh, Farajollah,Forozani, Mehdi,Taheri, Azam

, p. 1187 - 1189 (2007)

A new ionic liquid is presented as a med...

Integrated Electro-Biocatalysis for Amine Alkylation with Alcohols

Pe?afiel, Itziar,Dryfe, Robert A. W.,Turner, Nicholas J.,Greaney, Michael F.

, p. 864 - 867 (2021)

The integration of electro and bio-catal...

A general approach to mono- and bimetallic organometallic nanoparticles

Mavila, Sudheendran,Rozenberg, Illya,Lemcoff, N. Gabriel

, p. 4196 - 4203 (2014)

A comprehensive methodology to prepare n...

One-pot reductive amination of aldehydes and ketones with α-picoline-borane in methanol, in water, and in neat conditions

Sato, Shinya,Sakamoto, Takeshi,Miyazawa, Etsuko,Kikugawa, Yasuo

, p. 7899 - 7906 (2004)

A one-pot reductive amination of aldehyd...

A new method for deprotection of benzothiazolesulfonamides using a thiol and base

Wuts, Peter G. M.,Gu, Rui Lin,Northuis, Jill M.,Thomas, Collette L.

, p. 9155 - 9156 (1998)

Benzothiazolesulfonamides of primary and...

Highly economical and direct amination of sp3carbon using low-cost nickel pincer catalyst

Brandt, Andrew,Rangumagar, Ambar B.,Szwedo, Peter,Wayland, Hunter A.,Parnell, Charlette M.,Munshi, Pradip,Ghosh, Anindya

, p. 1862 - 1874 (2021)

Developing more efficient routes to achi...

Graphene-supported NiPd alloy nanoparticles: A novel and highly efficient heterogeneous catalyst system for the reductive amination of aldehydes

Ni?anci, Bilal,Ganjehyan, Khadijeh,Metin, ?nder,Da?tan, Arif,T?r?k, Béla

, p. 191 - 197 (2015)

A novel and highly efficient heterogeneo...

The use of a continuous flow-reactor employing a mixed hydrogen-liquid flow stream for the efficient reduction of imines to amines

Saaby, Steen,Knudsen, Kristian Rahbek,Ladlow, Mark,Ley, Steven V.

, p. 2909 - 2911 (2005)

Imines have been reduced to amines in hi...

Triazolylidene-Iridium Complexes with a Pendant Pyridyl Group for Cooperative Metal–Ligand Induced Catalytic Dehydrogenation of Amines

Valencia, Marta,Pereira, Ana,Müller-Bunz, Helge,Belderraín, Tomás R.,Pérez, Pedro J.,Albrecht, Martin

, p. 8901 - 8911 (2017)

Two iridium(III) complexes containing a ...

Air Stable Iron(II) PNP Pincer Complexes as Efficient Catalysts for the Selective Alkylation of Amines with Alcohols

Mastalir, Matthias,St?ger, Berthold,Pittenauer, Ernst,Puchberger, Michael,Allmaier, Günter,Kirchner, Karl

, p. 3824 - 3831 (2016)

A series of well-defined iron(II) comple...

Copper-Catalyzed Enantioselective Addition of Styrene-Derived Nucleophiles to Imines Enabled by Ligand-Controlled Chemoselective Hydrocupration

Yang, Yang,Perry, Ian B.,Buchwald, Stephen L.

, p. 9787 - 9790 (2016)

The copper-catalyzed intermolecular enan...

A Mild, Pyridine-Borane-Based Reductive Amination Protocol

Bomann, Mark D.,Guch, Ian C.,DiMare, Marcello

, p. 5995 - 5996 (1995)

Utilization of lithium triethylborohydride as a selective N-acyl deprotecting agent

Tanaka, Hideyuki,Ogasawara, Kunio

, p. 4417 - 4420 (2002)

Lithium triethylborohydride has been fou...

Novel simple thioureas with growth hormone releasing properties

Ankersen,Hansen, B. Sehested

, p. 631 - 635 (1997)

A series of thioureas containing two aro...

Cobalt-catalyzed transfer hydrogenation of C=O and C=N bonds

Zhang, Guoqi,Hanson, Susan K.

, p. 10151 - 10153 (2013)

An earth-abundant metal cobalt catalyst ...

Highly Selective, Efficient Deoxygenative Hydrogenation of Amides Catalyzed by a Manganese Pincer Complex via Metal-Ligand Cooperation

Zou, You-Quan,Chakraborty, Subrata,Nerush, Alexander,Oren, Dror,Diskin-Posner, Yael,Ben-David, Yehoshoa,Milstein, David

, p. 8014 - 8019 (2018)

Deoxygenative hydrogenation of amides to...

Iridium versus Iridium: Nanocluster and Monometallic Catalysts Carrying the Same Ligand Behave Differently

Cano, Israel,Martínez-Prieto, Luis M.,Chaudret, Bruno,van Leeuwen, Piet W. N. M.

, p. 1444 - 1450 (2017)

A specific secondary phosphine oxide (SP...

Transfer hydrogenation of imines with ammonia-borane: A concerted double-hydrogen-transfer reaction

Yang, Xianghua,Zhao, Lili,Fox, Thomas,Wang, Zhi-Xiang,Berke, Heinz

, p. 2058 - 2062 (2010)

(Chemical Equation Presented) Direct tra...

-

Axenrod,Milne

, p. 5775,5781 (1968)

General and Chemoselective Copper Oxide Catalysts for Hydrogenation Reactions

Li, Wu,Cui, Xinjiang,Junge, Kathrin,Surkus, Annette-Enrica,Kreyenschulte, Carsten,Bartling, Stephan,Beller, Matthias

, p. 4302 - 4307 (2019)

Copper oxide catalysts have been prepare...

Protocol for Visible-Light-Promoted Desulfonylation Reactions Utilizing Catalytic Benzimidazolium Aryloxide Betaines and Stoichiometric Hydride Donor Reagents

Hasegawa, Eietsu,Tanaka, Tsukasa,Izumiya, Norihiro,Kiuchi, Takehiro,Ooe, Yuuki,Iwamoto, Hajime,Takizawa, Shin-Ya,Murata, Shigeru

, p. 4344 - 4353 (2020)

An unprecedented photocatalytic system c...

Reductive amination of aldehydes and amines with an efficient Pd/NiO catalyst

Yang, Huimin,Cui, Xinjiang,Deng, Youquan,Shi, Feng

, p. 1314 - 1322 (2014)

By applying a simple Pd/NiO catalyst, th...

Indium-catalyzed reduction of secondary amides with a hydrosiloxane leading to secondary amines

Sakai, Norio,Takeoka, Masashi,Kumaki, Takayuki,Asano, Hirotaka,Konakahara, Takeo,Ogiwara, Yohei

, p. 6448 - 6451 (2015)

Described herein is that the selective r...

Oxidative deamination of benzylamine by electrogenerated quinonoid systems as mimics of amine oxidoreductases cofactors

Largeron,Fleury

, p. 8874 - 8881 (2000)

The reactions of a new type of quinonoid...

Easy microwave assisted deprotection of N-Boc derivatives

Siro, Jorge G.,Martín, Justina,García-Navío, José L.,Remui?an, Modesto J.,Vaquero, Juan J.

, p. 147 - 148 (1998)

A simple and efficient method for the cl...

The Effect of Phase-transfer Catalysis on Ammonolysis of Alkyl and Aryl Halides

Barak, Gabriela,Sasson, Yoel

, p. 1267 - 1268 (1987)

Quaternary ammonium salts improve the so...

Iron-catalyzed Cα-H oxidation of tertiary, aliphatic amines to amides under mild conditions

Legacy, Christopher J.,Wang, Anqi,O'Day, Brian J.,Emmert, Marion H.

, p. 14907 - 14910 (2015)

De novo syntheses of amides often genera...

Ketoester methacrylate resin, secondary amine clean-up in the presence of primary amines

Yu,Alesso,Pears,Worthington,Luke,Bradley

, p. 1947 - 1952 (2001)

A ketoester resin was developed as the b...

Hydrogenation of CO2, carbonyl and imine substrates catalyzed by [IrH3(PhPNHP)] complex

Ramaraj, Ayyappan,Nethaji, Munirathinam,Jagirdar, Balaji R.

, p. 25 - 34 (2019)

A series of iridium and rhodium complexe...

Deprotection of Arenesulfonamides with Samarium Iodide

Vedejs, Edwin,Lin, Shouzhong

, p. 1602 - 1603 (1994)

Deprotection of N-benzenesulfonamides or...

Catalyst-Free and Solvent-Free Facile Hydroboration of Imines

Pandey, Vipin K.,Donthireddy, Siva Nagendra Reddy,Rit, Arnab

, p. 3255 - 3258 (2019)

A facile process for the catalyst-free a...

An Improved Method for the Decyanation of N,N-Disubstituted Cyanamides

Misner, Jerry W.

, p. 3166 - 3168 (1987)

-

Hey,Ingold

, p. 66 (1933)

B(C6F5)3-catalyzed Hydrosilation of Imines via Silyliminium Intermediates

Blackwell, James M.,Sonmor, Eric R.,Scoccitti, Tiziana,Piers, Warren E.

, p. 3921 - 3923 (2000)

formula presented A broad range of benza...

Hemilabile N-heterocyclic carbene (NHC)-nitrogen-phosphine mediated Ru (II)-catalyzed N-alkylation of aromatic amine with alcohol efficiently

Yu, Xiao-Jun,He, Hai-Yu,Yang, Lei,Fu, Hai-Yan,Zheng, Xue-Li,Chen, Hua,Li, Rui-Xiang

, p. 54 - 57 (2017)

Based on the hemilability, a novel N-het...

Ni-Cu/γ-Al2O3 catalyzed N-alkylation of amines with alcohols

Sun, Jian,Jin, Xiaodong,Zhang, Fengwei,Hu, Wuquan,Liu, Juntao,Li, Rong

, p. 30 - 33 (2012)

A γ-Al2O3 supported Ni and Cu bimetallic...

Five-Coordinate Low-Spin {FeNO}7 PNP Pincer Complexes

Pecak, Jan,St?ger, Berthold,Mastalir, Matthias,Veiros, Luis F.,Ferreira, Liliana P.,Pignitter, Marc,Linert, Wolfgang,Kirchner, Karl

, p. 4641 - 4646 (2019)

The synthesis and characterization of ai...

The hydrosilylation of aid- and ketimines catalyzed by titanocene complexes

Tillack, Annegret,Lefeber, Claudia,Peulecke, Normen,Thomas, Dominique,Rosenthal, Uwe

, p. 1533 - 1534 (1997)

Different titanocene complexes 1-10 were...

Nickel-Catalyzed Hydrophosphonylation and Hydrogenation of Aromatic Nitriles Assisted by Lewis Acid

Islas, Rosa E.,García, Juventino J.

, p. 1337 - 1345 (2019)

In this paper, we describe the catalytic...

A mild, convenient, and inexpensive method for converting imines into amines: Tin-catalyzed reduction with polymethylhydrosiloxane (PMHS)

Lopez, Rosa M.,Fu, Gregory C.

, p. 16349 - 16354 (1997)

We have developed a mild, convenient, an...

Improving the industrial feasibility of metal-free hydrogenation catalysts using chemical scavengers

Thomson, Jordan W.,Hatnean, Jillian A.,Hastie, Jeff J.,Pasternak, Andrew,Stephan, Douglas W.,Chase, Preston A.

, p. 1287 - 1292 (2013)

A modified process using inexpensive poi...

TITANIUM(III) INDUCED TRANSFORMATIONS OF N,N-DISUBSTITUTED HYDROXYLAMINES TO IMINES AND SECONDARY AMINES

Murahashi, Shun-Ichi,Kodera, Yoichi

, p. 4633 - 4636 (1985)

The reaction of N,N-disubstituted hydrox...

Highly chemoselective reductive amination-coupling by one-pot reaction of aldehydes, HMDS and NaBH4

Azizi, Najmedin,Akbari, Elham,Amiri, Alireza Khejeh,Saidi, Mohammad R.

, p. 6682 - 6684 (2008)

An efficient and highly chemoselective s...

Silver nanoparticles supported on alumina-a highly efficient and selective nanocatalyst for imine reduction

Poreddy, Raju,Garcia-Suarez, Eduardo J.,Riisager, Anders,Kegnaes, Soren

, p. 4255 - 4259 (2014)

Silver nanoparticles supported on alumin...

-

Richey,Erickson

, p. 2807 (1972)

Ru(II) complexes containing (2-(pyren-1-ylmethylene)hydrazinyl)benzothiazole: Synthesis, solid-state structure, computational study and catalysis in N-alkylation reactions

Murugan, Kaliyappan,Ojwach, Stephen O.,Saravanan, Kandasamy,Vijayan, Paranthaman,Vijayapritha, Subbarayan,Viswanathamurthi, Periasamy

, (2020)

Reactions of (2-(pyren-1-ylmethylene)hyd...

Trichlorosilane-dimethylformamide (Cl3SiH-DMF) as an efficient reducing agent. Reduction of aldehydes and imines and reductive amination of aldehydes under mild conditions using hypervalent hydridosilicates

Kobayashi, Shu,Yasuda, Masaru,Hachiya, Iwao

, p. 407 - 408 (1996)

Trichlorosilane-dimethylformamide (Cl3Si...

A comparative analysis of hydrosilative amide reduction catalyzed by first-row transition metal (Mn, Fe, Co, and Ni): N -phosphinoamidinate complexes

Macaulay, Casper M.,Ogawa, Takahiko,McDonald, Robert,Sydora, Orson L.,Stradiotto, Mark,Turculet, Laura

, p. 9581 - 9587 (2019)

A comparative study of the performance o...

Visible Light and Hydroxynaphthylbenzimidazoline Promoted Transition-Metal-Catalyst-Free Desulfonylation of N-Sulfonylamides and N-Sulfonylamines

Hasegawa, Eietsu,Nagakura, Yuto,Izumiya, Norihiro,Matsumoto, Keisuke,Tanaka, Tsukasa,Miura, Tomoaki,Ikoma, Tadaaki,Iwamoto, Hajime,Wakamatsu, Kan

, p. 10813 - 10825 (2018)

A visible light promoted process for des...

Ultrasound-assisted synthesis of UiO-66-NHSO3H via post-synthetic modification as a heterogeneous Br?nsted acid catalyst

Homaee, Mahsa,Hamadi, Hosein,Nobakht, Valiollah,Javaherian, Mohammad,Salahshournia, Behrang

, p. 152 - 161 (2019)

Efficient SO3H-functionalized metal orga...

Tandem Fe/Zn or Fe/In Catalysis for the Selective Synthesis of Primary and Secondary Amines?via Selective Reduction of Primary Amides

Darcel, Christophe,Wu, Jiajun

, (2022/03/18)

Tandem iron/zinc or iron/indium-catalyse...

Nickel Complexes Bearing N,N,O-Tridentate Salicylaldiminato Ligand: Efficient Catalysts for Imines Formation via Dehydrogenative Coupling of Primary Alcohols with Amines

Han, Zhangang,Hao, Zhiqiang,Lin, Jin,Lu, Guo-Liang,Zhang, Junhua,Zhang, Xiaoying

, p. 3843 - 3853 (2021/11/18)

Treatment of salicylaldiminato ligand L1...

Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex

Bera, Jitendra K.,Pandey, Pragati

supporting information, p. 9204 - 9207 (2021/09/20)

A terminal [Ni-OH] complex1, supported b...

Hydrogenation of Secondary Amides using Phosphane Oxide and Frustrated Lewis Pair Catalysis

K?ring, Laura,Sitte, Nikolai A.,Bursch, Markus,Grimme, Stefan,Paradies, Jan

, p. 14179 - 14183 (2021/09/03)

The metal-free catalytic hydrogenation o...

103-49-1 Process route

: 780-25-6
N-benzylidene benzylamine

: 98-86-2
acetophenone

: 98-85-1,13323-81-4
1-Phenylethanol

: 103-49-1
dibenzylamine

Conditions

Conditions	Yield
With tetrakis[3,5-bis(trifluoromethyl)phenyl]boric acid bis(diethyl ether) complex; C₃₂H₆₃CoNP₂Si; hydrogen; In tetrahydrofuran; at 25 ℃; for 21h; under 760.051 Torr;	40 %Chromat.