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Purity:99%
A novel series of potent and selective P...
The invention features 4-((phenoxyalkyl)...
(R)-{4-[2-ethoxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid
Conditions | Yield |
---|---|
With
lithium hydroxide;
In
tetrahydrofuran;
|
(R)-{4-[2-hydroxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: NaH
2: aq. LiOH / tetrahydrofuran
With
lithium hydroxide; sodium hydride;
In
tetrahydrofuran;
|
(R)-{4-[2-ethoxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
(S)-2-((4-(trifluoromethyl)phenoxy)methyl)oxirane
(R)-{4-[2-hydroxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
4-hydroxybenzotrifluoride
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