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851528-79-5

  • Product Name:MBX 8025
  • Molecular Weight:444.472
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Product Details

Purity:99%

Export Top Purity MBX 8025 851528-79-5 In Stock

  • Molecular Formula:C21H23F3O5S
  • Molecular Weight:444.472

851528-79-5 Relevant articles

Discovery of para-alkylthiophenoxyacetic acids as a novel series of potent and selective PPARδ agonists

Zhang, Rui,Wang, Aihua,DeAngelis, Alan,Pelton, Patricia,Xu, Jun,Zhu, Peifang,Zhou, Lubing,Demarest, Keith,Murray, William V.,Kuo, Gee-Hong

, p. 3855 - 3859 (2008/02/13)

A novel series of potent and selective P...

4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS

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Page/Page column 74-75; 76, (2010/02/11)

The invention features 4-((phenoxyalkyl)...

851528-79-5 Process route

(R)-{4-[2-ethoxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
851528-83-1

(R)-{4-[2-ethoxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester

(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid
851528-79-5

(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid

Conditions
Conditions Yield
With lithium hydroxide; In tetrahydrofuran;
 
(R)-{4-[2-hydroxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester
851528-81-9

(R)-{4-[2-hydroxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester

(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid
851528-79-5

(R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)-sulfanyl)-2-methylphenoxy)acetic acid

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: NaH
2: aq. LiOH / tetrahydrofuran
With lithium hydroxide; sodium hydride; In tetrahydrofuran;
 

851528-79-5 Upstream products

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    (S)-2-((4-(trifluoromethyl)phenoxy)methyl)oxirane

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    851528-81-9

    (R)-{4-[2-hydroxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-acetic acid ethyl ester

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