What is the RAS-2410 hydrochloride?

RAS-2410 hydrochloride is , while it's Molecular Formula is C16H19N3O4S.HCl. Used in Oncology: RAS-2410 hydrochloride is used as an anticancer agent for the treatment of multiple myeloma. It works by inhibiting the activity of histone deacetylases, leading to hyperacetylation of histone H4 and the subsequent abrogation of cell growth and induction of apoptosis in multiple myeloma cells. Used in Combination Therapy: RAS-2410 hydrochloride is used as a synergistic agent in combination with melphalan, bortezomib, and S-2209 to enhance the therapeutic effects against multiple myeloma. The combination therapy aims to improve treatment outcomes and potentially overcome drug resistance in cancer cells. Used in Drug Development: RAS-2410 hydrochloride is used as a research compound for the development of novel histone deacetylase inhibitors. Its ability to inhibit HDAC activity in vivo makes it a valuable tool for studying the role of HDACs in various diseases and for designing new therapeutic strategies targeting these enzymes.

What is the CAS number for RAS-2410 hydrochloride?

The CAS number of RAS-2410 hydrochloride is 1187075-34-8.

What is RAS-2410 hydrochloride (1187075-34-8) used for?

Resminostat is an orally bioavailable inhibitor of histone deacetylase 1 (HDAC1), HDAC3, and HDAC6 (IC50s = 43-72 nM), resulting in hyperacetylation of histone H4 in multiple myeloma cells. It abrogates cell growth and strongly induces apoptosis in multiple myeloma cells (IC50s = 2.5-3 μM). Resminostat displays synergistic effects when combined with melphalan and the proteasome inhibitors bortezomib and S-2209. It dose-dependently inhibits HDAC activity in vivo.

What is the RAS-2410 hydrochloride?

RAS-2410 hydrochloride is , while it's Molecular Formula is C16H19N3O4S.HCl. Used in Oncology: RAS-2410 hydrochloride is used as an anticancer agent for the treatment of multiple myeloma. It works by inhibiting the activity of histone deacetylases, leading to hyperacetylation of histone H4 and the subsequent abrogation of cell growth and induction of apoptosis in multiple myeloma cells. Used in Combination Therapy: RAS-2410 hydrochloride is used as a synergistic agent in combination with melphalan, bortezomib, and S-2209 to enhance the therapeutic effects against multiple myeloma. The combination therapy aims to improve treatment outcomes and potentially overcome drug resistance in cancer cells. Used in Drug Development: RAS-2410 hydrochloride is used as a research compound for the development of novel histone deacetylase inhibitors. Its ability to inhibit HDAC activity in vivo makes it a valuable tool for studying the role of HDACs in various diseases and for designing new therapeutic strategies targeting these enzymes.

What is the CAS number for RAS-2410 hydrochloride?

The CAS number of RAS-2410 hydrochloride is 1187075-34-8.

What is RAS-2410 hydrochloride (1187075-34-8) used for?

Resminostat is an orally bioavailable inhibitor of histone deacetylase 1 (HDAC1), HDAC3, and HDAC6 (IC50s = 43-72 nM), resulting in hyperacetylation of histone H4 in multiple myeloma cells. It abrogates cell growth and strongly induces apoptosis in multiple myeloma cells (IC50s = 2.5-3 μM). Resminostat displays synergistic effects when combined with melphalan and the proteasome inhibitors bortezomib and S-2209. It dose-dependently inhibits HDAC activity in vivo.

Product classification

Contact us

Tel：+86-0533-2185556
Fax：+86-0533-2185556
Phone：+86 15965530500
Website：http://www.shandonghangyu.com/
Email：admin@hangyubiotech.com
Address：Room 2516, Dingcheng Building, Beijing Road, Zhangdian District, Zibo City, Shandong Province

1187075-34-8

Product Name:RAS-2410 hydrochloride
Molecular Formula:C16H20ClN3O4S
Molecular Weight:385.871

Inquiry

Product Details

Purity:99%

Manufacturer supply RAS-2410 hydrochloride 1187075-34-8 with sufficient stock and high standard

Molecular Formula:C16H19N3O4S.HCl
Molecular Weight:385.871
PSA：100.02000
LogP:3.57900

1187075-34-8 Relevant articles

Novel method for the production of sulphonylpyrroles as HDAC inhibitors

-

Page/Page column 10, (2009/09/28)

Process for the preparation of a compoun...

1187075-34-8 Process route

: 1187075-38-2
(E)-3-[1-(4-dimethylaminomethyl-benzenesulfonyl)-1H-pyrrol-3-yl]-acryloyl chloride hydrochloride

: 1187075-34-8
(E)-3-[1-(4-dimethylaminomethyl-benzenesulfonyl)-1H-pyrrol-3-yl]N-hydroxy-acrylamide hydrochloride

Conditions

Conditions	Yield
With hydroxylamine; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; water; at 18 - 30 ℃; Industry scale;

1187075-34-8 Upstream products

1187075-38-2
(E)-3-[1-(4-dimethylaminomethyl-benzenesulfonyl)-1H-pyrrol-3-yl]-acryloyl chloride hydrochloride

Relevant Products

Prasugrel
CAS：115473-15-9
marineblau 018112
CAS：118685-33-9
2,2'-(Thiocarbonylbis(sulfanediyl))bis(2-methylpropanoic acid)
CAS：355120-40-0
SU 6656
CAS：330161-87-0

Home

About us

Products

small-molecule inhibitor

intermediate

Pharmaceutical intermediate

Biochemical reagent

fire retardant

chemical reagent

ionic liquid

API

Pharmaceutical intermediates

Biological products

Polypeptides

Chemical reagents

Small molecule inhibitors

Organic electronic chemical materials

Technical Support

News

Contact Us