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The present invention provides compounds...
The present invention relates to a compo...
2-chloro-5-?uoropyridine-6-carboxylic acid
methyl iodide
methyl 6-chloro-3-fluoropyridine-2-carboxylate
| Conditions | Yield |
|---|---|
|
With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h;
|
59.73% |
methanol
2-chloro-5-?uoropyridine-6-carboxylic acid
methyl 6-chloro-3-fluoropyridine-2-carboxylate
| Conditions | Yield |
|---|---|
|
methanol; 2-chloro-5-?uoropyridine-6-carboxylic acid; With sulfuric acid; for 2.5h; Heating; Reflux;
With sodium hydroxide; In water;
|
methanol
2-chloro-5-?uoropyridine-6-carboxylic acid
methyl iodide
C13H10ClNO3
1-[(6-[(4-methoxyphenyl)amino]-3-{[6-(methylsulfonyl)pyridin-3-yl]oxy}pyridin-2-yl)methyl]pyrrolidin-2-one
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