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Purity:99%
Through the intramolecular cyclization o...
The invention relates to a substituted p...
A newly developed chemoselective reactio...
One-step, catalytic synthesis of N-aryls...
Methyl 3-aminobenzoate
p-toluenesulfonyl chloride
methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate
Conditions | Yield |
---|---|
With
pyridine; dmap;
In
dichloromethane;
at 20 ℃;
|
99% |
Yield given. Multistep reaction;
|
|
With
pyridine;
In
dichloromethane;
at 0 - 20 ℃;
for 1h;
|
methyl 3-nitrobenzoate
sodium 4-methylbenzenesulfinate
methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate
Conditions | Yield |
---|---|
With
trans-N,N'-dimethyl-1,2-cyclohexyldiamine; sodium hydrogen sulfite; iron(II) chloride;
In
dimethyl sulfoxide;
at 60 ℃;
for 12h;
Sealed tube;
Inert atmosphere;
|
95% |
With
sodium hydrogensulfite;
In
water;
at 60 ℃;
for 20h;
chemoselective reaction;
|
86% |
Methyl 3-aminobenzoate
p-toluenesulfonyl chloride
methyl 3-iodo-benzoate
toluene-4-sulfonamide
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