What is the (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide?

(1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is , while it's Molecular Formula is C 33 H 41 ClN 2 O 5 S. Used in Pharmaceutical Industry: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is used as a potential pharmaceutical agent for its unique and complex structure, which may offer novel therapeutic properties and applications in the development of new drugs. Used in Chemical Research: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is utilized in chemical research as a model for studying the synthesis, reactivity, and properties of spirooxathiadiazatetracyclic systems, providing insights into the development of new synthetic routes and potential applications in various chemical processes. Used in Biological Research: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide serves as a valuable tool in biological research, particularly in the study of molecular interactions, biological activity, and potential therapeutic effects in various biological systems.

What is the CAS number for (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide?

The CAS number of (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is 1883727-34-1.

What is (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide (1883727-34-1) used for?

(1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is a complex organic compound characterized by its unique spirooxathiadiazatetracyclic structure. It features a chlorine atom, a methoxy group, and two methyl groups, as well as a variety of fused ring systems, including naphthalene, oxathiadiazatetracyclo, and tetracyclo. (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide has the potential for pharmacological and therapeutic applications due to its distinctive and intricate molecular architecture, and it may also exhibit intriguing properties for use in chemical and biological research.

What is the (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide?

(1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is , while it's Molecular Formula is C 33 H 41 ClN 2 O 5 S. Used in Pharmaceutical Industry: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is used as a potential pharmaceutical agent for its unique and complex structure, which may offer novel therapeutic properties and applications in the development of new drugs. Used in Chemical Research: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is utilized in chemical research as a model for studying the synthesis, reactivity, and properties of spirooxathiadiazatetracyclic systems, providing insights into the development of new synthetic routes and potential applications in various chemical processes. Used in Biological Research: (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide serves as a valuable tool in biological research, particularly in the study of molecular interactions, biological activity, and potential therapeutic effects in various biological systems.

What is the CAS number for (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide?

The CAS number of (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is 1883727-34-1.

What is (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide (1883727-34-1) used for?

(1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide is a complex organic compound characterized by its unique spirooxathiadiazatetracyclic structure. It features a chlorine atom, a methoxy group, and two methyl groups, as well as a variety of fused ring systems, including naphthalene, oxathiadiazatetracyclo, and tetracyclo. (1S,3’R,6’R,7’R,8’E,11’S,12’R)-6-chloro-7'-methoxyl-11',12'-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[8,16,18,24]tetraen]-15'-one-13',13'-dioxide has the potential for pharmacological and therapeutic applications due to its distinctive and intricate molecular architecture, and it may also exhibit intriguing properties for use in chemical and biological research.

Product classification

Contact us

Tel：+86-0533-2185556
Fax：+86-0533-2185556
Phone：+86 15965530500
Website：http://www.shandonghangyu.com/
Email：admin@hangyubiotech.com
Address：Room 2516, Dingcheng Building, Beijing Road, Zhangdian District, Zibo City, Shandong Province

1883727-34-1

Product Name:AMG-176
Molecular Weight:613.218

Inquiry

Product Details

Purity:99%

Manufacturer supply high quality AMG-176 1883727-34-1 with GMP standards

Molecular Formula:C₃₃H₄₁ClN₂O₅S
Molecular Weight:613.218
Density:1.32±0.1 g/cm3(Predicted)

1883727-34-1 Relevant articles

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

-

, (2017/09/15)

Provided herein are myeloid cell leukemi...

TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN

-

, (2016/03/22)

Provided herein are myeloid cell leukemi...

1883727-34-1 Process route

: 4462-96-8
cis-1,2-cyclobutane dicarboxylic anhydride

: 1883727-34-1
(1S,3’R,6’R,7’S,9’E,11’S,12’R)-6-chloro-7'-methoxy-11’,12’-dimethyl-3,4-dihydro-2H,15’H-spiro[naphthalene-1,22’-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.03,6.019,24]pentacosa[9,16,18,24]tetraen]-15’-one-13’,13'-dioxide

Conditions

Conditions	Yield
Multi-step reaction with 12 steps 1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere 2.1: 50 °C 3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction 4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C 4.2: 48 h / 1.8 - 20 °C 5.1: dichloromethane; acetic acid / 0.17 h / 20 °C 5.2: 1.17 h / 0 °C 6.1: potassium hydroxide / methanol / 4 h / 20 °C 6.2: pH 7 7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere 8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C 8.2: 0 h / -10 - -5 °C 9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C 9.2: 0 °C / pH 3 10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C 11.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 15 h / 45 °C / Inert atmosphere 12.1: potassium hexamethylsilazane / tetrahydrofuran; 2-methyltetrahydrofuran / 2 h / -44 - 20 °C / Inert atmosphere With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; lithium aluminium tetrahydride; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; potassium hexamethylsilazane; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; 2-methyltetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; toluene;
Multi-step reaction with 12 steps 1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere 2.1: 50 °C 3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction 4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C 4.2: 48 h / 1.8 - 20 °C 5.1: dichloromethane; acetic acid / 0.17 h / 20 °C 5.2: 1.17 h / 0 °C 6.1: potassium hydroxide / methanol / 4 h / 20 °C 6.2: pH 7 7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere 8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C 8.2: 0 h / -10 - -5 °C 9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C 9.2: 0 °C / pH 3 10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C 11.1: Hoveyda-Grubbs catalyst second generation / 1,2-dichloro-ethane / 10 h / 60 °C / Inert atmosphere 11.2: 20 °C 12.1: potassium hexamethylsilazane / tetrahydrofuran; 2-methyltetrahydrofuran / 2 h / -44 - 20 °C / Inert atmosphere With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; lithium aluminium tetrahydride; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; potassium hexamethylsilazane; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; 2-methyltetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; 1,2-dichloro-ethane; toluene;

Yield

Multi-step reaction with 12 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere

2.1: 50 °C

3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction

4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C

4.2: 48 h / 1.8 - 20 °C

5.1: dichloromethane; acetic acid / 0.17 h / 20 °C

5.2: 1.17 h / 0 °C

6.1: potassium hydroxide / methanol / 4 h / 20 °C

6.2: pH 7

7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere

8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C

8.2: 0 h / -10 - -5 °C

9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C

9.2: 0 °C / pH 3

10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

11.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 15 h / 45 °C / Inert atmosphere

12.1: potassium hexamethylsilazane / tetrahydrofuran; 2-methyltetrahydrofuran / 2 h / -44 - 20 °C / Inert atmosphere

With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; lithium aluminium tetrahydride; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; potassium hexamethylsilazane; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; 2-methyltetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; toluene;

Multi-step reaction with 12 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere

2.1: 50 °C

3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction

4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C

4.2: 48 h / 1.8 - 20 °C

5.1: dichloromethane; acetic acid / 0.17 h / 20 °C

5.2: 1.17 h / 0 °C

6.1: potassium hydroxide / methanol / 4 h / 20 °C

6.2: pH 7

7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere

8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C

8.2: 0 h / -10 - -5 °C

9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C

9.2: 0 °C / pH 3

10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

11.1: Hoveyda-Grubbs catalyst second generation / 1,2-dichloro-ethane / 10 h / 60 °C / Inert atmosphere

11.2: 20 °C

12.1: potassium hexamethylsilazane / tetrahydrofuran; 2-methyltetrahydrofuran / 2 h / -44 - 20 °C / Inert atmosphere

: 4462-96-8
cis-1,2-cyclobutane dicarboxylic anhydride

: 1883727-34-1
(1S,3'R,6'R,7'S,8'Z,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H,15'H-spiro[naphthalene-1,22'-[20]oxa[13]thia[1,14]diazatetracyclo[14.7.2.0³'⁶.0¹⁹'²⁴]pentacosa[8,16,18,24]tetraen]-15'-one 13',13'-dioxide

Conditions

Conditions	Yield
Multi-step reaction with 12 steps 1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere 2.1: 50 °C 3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction 4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C 4.2: 48 h / 1.8 - 20 °C 5.1: dichloromethane; acetic acid / 0.17 h / 20 °C 5.2: 1.17 h / 0 °C 6.1: potassium hydroxide / methanol / 4 h / 20 °C 6.2: pH 7 7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere 8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C 8.2: 0 h / -10 - -5 °C 9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C 9.2: 0 °C / pH 3 10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C 11.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 15 h / 45 °C / Inert atmosphere 12.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C 12.2: 1 h / 20 °C With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; lithium aluminium tetrahydride; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; sodium hydride; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; toluene; mineral oil;

Yield

Multi-step reaction with 12 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 20 - 50 °C / Inert atmosphere

2.1: 50 °C

3.1: sodium citrate / water / 0.2 °C / pH Ca₅₄₅ / Enzymatic reaction

4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 15 - 20 °C

4.2: 48 h / 1.8 - 20 °C

5.1: dichloromethane; acetic acid / 0.17 h / 20 °C

5.2: 1.17 h / 0 °C

6.1: potassium hydroxide / methanol / 4 h / 20 °C

6.2: pH 7

7.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 2.5 h / -70 °C / Inert atmosphere

8.1: (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; n-butyllithium / toluene; hexane / 1 h / 0 - 12 °C

8.2: 0 h / -10 - -5 °C

9.1: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 4 h / 50 °C

9.2: 0 °C / pH 3

10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0 - 20 °C

11.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 15 h / 45 °C / Inert atmosphere

12.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C

12.2: 1 h / 20 °C

With dmap; (1R,2S)-2-(morpholin-4-yl)-1-phenyl-1-propanol; lithium aluminium tetrahydride; n-butyllithium; Hoveyda-Grubbs catalyst second generation; oxalyl dichloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; lithium hydroxide monohydrate; [bis(acetoxy)iodo]benzene; water; sodium citrate; sodium hydride; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetic acid; toluene; mineral oil;

1883727-34-1 Upstream products

74-88-4
methyl iodide
125225-80-1
(2S,3S)-3-Methyl-5-hexen-2-ol
453-71-4
3-nitro-4-fluorobenzoic acid
579514-75-3
tert-butyl 4-fluoro-3-nitrobenzoate

Relevant Products

C646
CAS：328968-36-1
dibutyl terephthalate
CAS：1962-75-0
N-OCTYL METHACRYLATE
CAS：2157-01-9
Monochlorotriazinyl--cyclodextrin
CAS：187820-08-2

Home

About us

Products

small-molecule inhibitor

intermediate

Pharmaceutical intermediate

Biochemical reagent

fire retardant

chemical reagent

ionic liquid

API

Pharmaceutical intermediates

Biological products

Polypeptides

Chemical reagents

Small molecule inhibitors

Organic electronic chemical materials

Technical Support

News

Contact Us

Inquiry

Product classification

Contact us

1883727-34-1

Product Details

Manufacturer supply high quality AMG-176 1883727-34-1 with GMP standards

1883727-34-1 Relevant articles

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

-

, (2017/09/15)

TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN

-

, (2016/03/22)

1883727-34-1 Process route

1883727-34-1 Upstream products

Relevant Products