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pd_meltingpoint:140 - 142oC
Appearance:White powder
Purity:99%
β-Nicotinamide adenine dinucleotide Good Supplier In Bulk Supply High Purity 53-84-9 We provide high quality beta-Diphosphopyridine nucleotide (CAS 53-84-9), at a very affordable prices to our customers.
β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.
β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a c oenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleot ide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
The CAS number of beta-Diphosphopyridine nucleotide is 53-84-9.
More information of beta-Diphosphopyridine nucleotide 53-84-9 are:
CAS Number |
53-84-9 |
Melting Point |
140 - 142oC |
HS CODE |
29349990 |
PSA |
340.71000 |
LogP |
-1.29620 |
The chemical formula of beta-Diphosphopyridine nucleotide is C21H27N7O14P2 which containing 21 Carbon atoms,27 Hydrogen atoms,7 Nitrogen atoms,14 Oxygen atoms and 2 Phosphorus atoms,and the molecular weight, and the molecular weight of beta-Diphosphopyridine nucleotide is 663.431
β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.
InChI:InChI=1/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/p-1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
Relevant articles related to beta-Diphosphopyridine nucleotide:
Article |
Source |
Oxygen Activation and Electron Transfer in Flavocytochrome P450 BM3 |
Ost, Tobias W. B.,Clark, Jonathan,Mowat, Christopher G.,Miles, Caroline S.,Walkinshaw, Malcolm D.,Reid, Graeme A.,Chapman, Stephen K.,Daff, Simon , p. 15010 - 15020 (2003) |
NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: Insight into its biological role |
Cortial, Sylvie,Chaignon, Philippe,Iorga, Bogdan I.,Aymerich, Stephane,Truan, Gilles,Gueguen-Chaignon, Virginie,Meyer, Philippe,Morera, Solange,Ouazzani, Jamal , p. 3916 - 3922 (2010) |
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