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pd_meltingpoint:209-212oC
Purity:99%
Definition |
ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit. |
InChI:InChI=1/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
The invention provides a simple preparat...
The invention relates to the use of cert...
Methods of stimulating an immune respons...
The invention relates to methods for the...
bromochlorobenzene
1-amino-4-(pyridin-4-yl)methylpyridazine
vatalanib
Conditions | Yield |
---|---|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 110 - 115 ℃;
for 5h;
Temperature;
|
92.8% |
1-Chloro-4-iodobenzene
1-amino-4-(pyridin-4-yl)methylpyridazine
vatalanib
Conditions | Yield |
---|---|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 100 - 105 ℃;
for 5h;
|
93.4% |
4-chloro-aniline
5-(pyridin-4-yl)methyl-2H-phthalazin-1-one
2-benzofuran-1(3H)-one
3-hydroxy-2-(pyridin-4-yl)-1H-inden-1-one
ZK 228354
1-(4-Chlor-anilino)-4-(pyridin-4-yl-fluormethyl)-phthalazine
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