2438-80-4

  • Product Name:L-Fucose
  • Molecular Formula:C6H12O5
  • Molecular Weight:164.158
  • Appearance:White solid
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Product Details

pd_meltingpoint:150-153 °C(lit.)

Appearance:White solid

Purity:99%

Top Quality Chinese Factory supply 2438-80-4 L-Fucose

  • Molecular Formula:C6H12O5
  • Molecular Weight:164.158
  • Appearance/Colour:White solid 
  • Vapor Pressure:5E-08mmHg at 25°C 
  • Melting Point:150-153 °C(lit.) 
  • Refractive Index:-75.5 ° (C=10, H2O) 
  • Boiling Point:399.1 °C at 760 mmHg 
  • PKA:12.50±0.20(Predicted) 
  • Flash Point:209.3 °C 
  • PSA:97.99000 
  • Density:1.41 g/cm3 
  • LogP:-2.35120 

L-FUCOSE(Cas 2438-80-4) Usage

Reactions

L-Fucose is oxidised by the enzyme L-fucose dehydrogenase in the presence of nicotinamide-adenine dinucleotide phosphate (NADP+) to L-fucono-1,5-lactone with the formation of reduced nicotinamideadenine dinucleotide phosphate (NADPH) (1).(L-fucose dehydrogenase) (1)L-Fucose + NADP+ --> L-fucono-1,5-lactone + NADPH + H+The amount of NADPH formed in this reaction is stoichiometric with the amount of L-fucose. It is the NADPH which is measured by the increase in absorbance at 340 nm.

Biological Activity

L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. It is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis.

Definition

ChEBI: L-fucopyranose is the pyranose form of L-fucose. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a L-fucose and a fucopyranose.

InChI:InChI=1/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1

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Purification and structural characteriza...

2438-80-4 Process route

(4-nitro-phenyl)-α-<i>L</i>-fucopyranoside
10231-84-2

(4-nitro-phenyl)-α-L-fucopyranoside

4-nitro-phenol
100-02-7,78813-13-5,89830-32-0

4-nitro-phenol

L-Fucose
2438-80-4,478518-52-4

L-Fucose

Conditions
Conditions Yield
With α-L-fucoside isolated from the liver of Venus mercenaria; sodium carbonate; In water; at 37 ℃; Rate constant; sodium citrat-dihydrogen phosphate buffer;
α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol
84012-04-4,117751-58-3

α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol

D-Galactose
10257-28-0

D-Galactose

L-Fucose
2438-80-4,478518-52-4

L-Fucose

2-acetamido-2-deoxy-D-galacticol
10486-91-6

2-acetamido-2-deoxy-D-galacticol

N-acetylgalactosamine
134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3

N-acetylgalactosamine

Conditions
Conditions Yield
With sodium tetrahydroborate; hydrazine; sodium nitrite; Product distribution; with or without hydrazinium sulfate: investigation of the hydrazinolysis-nitrous-deamination procedure; steric influence of the 3-O-substitution; mechanism is proposed;

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