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pd_meltingpoint:150-153 °C(lit.)
Appearance:White solid
Purity:99%
Reactions |
L-Fucose is oxidised by the enzyme L-fucose dehydrogenase in the presence of nicotinamide-adenine dinucleotide phosphate (NADP+) to L-fucono-1,5-lactone with the formation of reduced nicotinamideadenine dinucleotide phosphate (NADPH) (1).(L-fucose dehydrogenase) (1)L-Fucose + NADP+ --> L-fucono-1,5-lactone + NADPH + H+The amount of NADPH formed in this reaction is stoichiometric with the amount of L-fucose. It is the NADPH which is measured by the increase in absorbance at 340 nm. |
Biological Activity |
L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. It is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis. |
Definition |
ChEBI: L-fucopyranose is the pyranose form of L-fucose. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a L-fucose and a fucopyranose. |
InChI:InChI=1/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1
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(4-nitro-phenyl)-α-L-fucopyranoside
4-nitro-phenol
L-Fucose
Conditions | Yield |
---|---|
With
α-L-fucoside isolated from the liver of Venus mercenaria; sodium carbonate;
In
water;
at 37 ℃;
Rate constant;
sodium citrat-dihydrogen phosphate buffer;
|
α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol
D-Galactose
L-Fucose
2-acetamido-2-deoxy-D-galacticol
N-acetylgalactosamine
Conditions | Yield |
---|---|
With
sodium tetrahydroborate; hydrazine; sodium nitrite;
Product distribution;
with or without hydrazinium sulfate: investigation of the hydrazinolysis-nitrous-deamination procedure; steric influence of the 3-O-substitution; mechanism is proposed;
|
acetic acid
2′-fucosyllactose
(3S,4S,5R)-dihydro-3,4-dihydroxy-5-((1'S)-1'-hydroxyethyl)furan-2(3H)-one
α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol
D,L-rhamnose
Acetic acid (1R,2R,3R)-2,3-diacetoxy-1-{(R)-1-acetoxy-2-[acetyl-((S)-1-phenyl-ethyl)-amino]-ethyl}-butyl ester
trimethylsilyl ether of 6-deoxymannose-anti-O-benzyloxime
trimethylsilyl ether of 6-deoxymannose-syn-O-benzyloxime
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