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1089279-90-2

  • Product Name:1-(5-Methoxy-2-Methyl-4-nitrophenyl)-N,N-diMethylpiperidin-4-aMine
  • Molecular Weight:279.339
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Product Details

Purity:99%

Manufacturer Supply Best Quality 1-(5-Methoxy-2-Methyl-4-nitrophenyl)-N,N-diMethylpiperidin-4-aMine 1089279-90-2 with Efficient Transportation

  • Molecular Formula:C14H21N3O3
  • Molecular Weight:279.339
  • Boiling Point:437.4±45.0 °C(Predicted) 
  • PKA:9.14±0.20(Predicted) 
  • Density:1.19±0.1 g/cm3(Predicted) 

1089279-90-2 Relevant articles

Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing a sulfoxide moiety as anaplastic lymphoma kinase (ALK) inhibition agents

Wu, Feng,Yao, Han,Li, Wei,Zhang, Niuniu,Fan, Yangyang,Chan, Albert S.C.,Li, Xingshu,An, Baijiao

, (2021/07/19)

Anaplastic lymphoma kinase (ALK) targete...

N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER

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Paragraph 0125; 0126, (2020/05/07)

The present invention relates to a N2,N4...

PYRIMIDINE DERIVATIVE AND USE THEREOF

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Paragraph 0261; 0262; 0263, (2018/09/27)

The present invention provides a pyrimid...

2,4-dibasic miazines compound

-

Paragraph 0249; 0256; 0257; 0258, (2017/08/29)

The invention belongs to the field of me...

1089279-90-2 Process route

1-(3-methoxy-4 nitrophenyl)piperidin-4-one
761440-64-6

1-(3-methoxy-4 nitrophenyl)piperidin-4-one

dimethyl amine
124-40-3

dimethyl amine

1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidine-4-amine
1089279-90-2

1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidine-4-amine

Conditions
Conditions Yield
1-(3-methoxy-4 nitrophenyl)piperidin-4-one; dimethyl amine; With sodium tris(acetoxy)borohydride; acetic acid; In tetrahydrofuran; 1,2-dichloro-ethane;
With sodium hydrogencarbonate; In water; pH=> 7;
88%
With formic acid; trimethyl orthoformate; In tetrahydrofuran; at 70 ℃; for 7h;
75.04%
4-fluoro-2-methoxy-1-nitrobenzene
448-19-1

4-fluoro-2-methoxy-1-nitrobenzene

N,N-dimethylpiperidine-4-amine hydrochloride
172281-90-2

N,N-dimethylpiperidine-4-amine hydrochloride

1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidine-4-amine
1089279-90-2

1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidine-4-amine

Conditions
Conditions Yield
With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;
80%

1089279-90-2 Upstream products

  • 761440-64-6
    761440-64-6

    1-(3-methoxy-4 nitrophenyl)piperidin-4-one

  • 124-40-3
    124-40-3

    dimethyl amine

  • 50533-97-6
    50533-97-6

    dimethyl-piperidin-4-yl-amine

  • 448-19-1
    448-19-1

    4-fluoro-2-methoxy-1-nitrobenzene

1089279-90-2 Downstream products

  • 1089279-91-3
    1089279-91-3

    1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidine-4-amine

  • 1197958-12-5
    1197958-12-5

    (2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl )amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide

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