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Purity:99%
General Description |
2,6-Dimethoxyisonicotinic acid is a chemical compound with the molecular formula C9H9NO5. It is a derivative of isonicotinic acid, a commonly used building block in the synthesis of pharmaceuticals and agrochemicals. 2,6-Dimethoxyisonicotinic acid contains two methoxy (O-CH3) groups and one carboxylic acid (COOH) group, and its structure is characterized by a six-membered heterocyclic ring. 2,6-Dimethoxyisonicotinic acid has potential biological activities, including anti-tumor and anti-inflammatory effects, making it a subject of interest in medicinal chemistry and drug development. Its structural features allow for functionalization and modification, making it a versatile platform for the design of novel bioactive compounds. |
InChI:InChI=1/C8H9NO4/c1-12-6-3-5(8(10)11)4-7(9-6)13-2/h3-4H,1-2H3,(H,10,11)
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sodium methylate
2,6-dichloropyridine-4-carboxylic acid
2,6-dimethoxypyridine-4-carboxylic acid
Conditions | Yield |
---|---|
In
diethylene glycol dimethyl ether;
for 24h;
Reflux;
Dean-Stark;
|
66.4% |
In
methanol;
at 150 ℃;
for 4h;
Microwave irradiation;
|
methanol
2,6-dichloropyridine-4-carboxylic acid
2-chloro-6-methoxy-isonicotinic acid
2,6-dimethoxypyridine-4-carboxylic acid
Conditions | Yield |
---|---|
methanol; 2,6-dichloropyridine-4-carboxylic acid;
With
sodium hydroxide;
for 0.5h;
Heating / reflux;
With
hydrogenchloride;
In
water;
pH=4 - 6;
|
2,6-dichloropyridine-4-carboxylic acid
methanol
sodium methylate
2,6-dimethoxyisonicotinoyl chloride
2,6-dimethoxy-4-pyridinecarboxaldehyde
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