What is the LDN-192960?

LDN-192960 is , while it's Molecular Formula is C18H20N2O2S. 3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride, is an acridine analog, acting as haspin and DYRK2 kinase inhibitor. The studies has also shown that they can have antitrypanosomal and antiplasmid properties.

What is the CAS number for LDN-192960?

The CAS number of LDN-192960 is 184582-62-5.

What is LDN-192960 (184582-62-5) used for?

LDN-192960, also known as 3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride, is an acridine analog that functions as a haspin and DYRK2 kinase inhibitor. It has been found to possess antitrypanosomal and antiplasmid properties, making it a potential candidate for various applications in the pharmaceutical and medical fields.

What is the LDN-192960?

LDN-192960 is , while it's Molecular Formula is C18H20N2O2S. 3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride, is an acridine analog, acting as haspin and DYRK2 kinase inhibitor. The studies has also shown that they can have antitrypanosomal and antiplasmid properties.

What is the CAS number for LDN-192960?

The CAS number of LDN-192960 is 184582-62-5.

What is LDN-192960 (184582-62-5) used for?

LDN-192960, also known as 3-[(2,7-Dimethoxy-9-acridinyl)thio]-1-propanamine Hydrochloride, is an acridine analog that functions as a haspin and DYRK2 kinase inhibitor. It has been found to possess antitrypanosomal and antiplasmid properties, making it a potential candidate for various applications in the pharmaceutical and medical fields.

Product classification

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184582-62-5

Product Name:LDN-192960
Molecular Formula:C18H20N2O2S
Molecular Weight:328.43

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Product Details

Purity:99%

Reputable supplier selling LDN-192960 184582-62-5 with stock

Molecular Formula:C18H20N2O2S
Molecular Weight:328.43
Boiling Point:536.1±40.0 °C(Predicted)
PKA:9.33±0.10(Predicted)
PSA：82.67000
Density:1.25±0.1 g/cm3(Predicted)
LogP:4.54640

184582-62-5 Relevant articles

ACRIDINES AS INHIBITORS OF HASPIN AND DYRK KINASES

-

Page/Page column 28; 29; 32, (2011/10/31)

The present disclosure is directed to co...

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

Cuny, Gregory D.,Robin, Maxime,Ulyanova, Natalia P.,Patnaik, Debasis,Pique, Valerie,Casano, Gilles,Liu, Ji-Feng,Lin, Xiangjie,Xian, Jun,Glicksman, Marcie A.,Stein, Ross L.,Higgins, Jonathan M.G.

scheme or table, p. 3491 - 3494 (2010/08/21)

Haspin is a serine/threonine kinase requ...

184582-62-5 Process route

: C₁₅H₁₂NO₃

: 5003-71-4
3-bromopropylamine hydrochloride

: 184582-62-5
LDN-192960

Conditions

Conditions	Yield
C₁₅H₁₂NO₃; With Lawessons reagent; In tetrahydrofuran; at 110 ℃; microwave irradiation; 3-bromopropylamine hydrochloride; With phenol; at 80 ℃;

: C₂₃H₂₈N₂O₄S

: 184582-62-5
LDN-192960

Conditions

Conditions	Yield
With hydrogenchloride; methanol; In 1,4-dioxane; at 20 ℃;

184582-62-5 Upstream products

5003-71-4
3-bromopropylamine hydrochloride
104-94-9
4-methoxy-aniline

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