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Purity:99%
The efficient generation of novel, N-lin...
The present technology relates to compou...
Venezuelan equine encephalitis virus (VE...
tert-butyl N-methyl (2-(methyl((6-nitro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)methyl)amino)ethyl)carbamate
(E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-N-phenylbenzamide
| Conditions | Yield |
|---|---|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 0.75h;
|
49% |
|
Multi-step reaction with 2 steps
1: trifluoroacetic acid / dichloromethane / 0.75 h / 20 °C
2: alkaline salt / dichloromethane; water / pH 10
With
trifluoroacetic acid;
In
dichloromethane; water;
|
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 0.75h;
|
2-(chloromethyl)-6-nitro-3-phenylquinazolin-4(3H)-one
N,N`-dimethylethylenediamine
(E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-N-phenylbenzamide
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
acetonitrile;
at 50 ℃;
for 2h;
|
69% |
|
With
potassium carbonate;
In
acetonitrile;
at 50 ℃;
for 1h;
|
68% |
tert-butyl N-methyl (2-(methyl((6-nitro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)methyl)amino)ethyl)carbamate
2-amino-5-nitro-benzoic acid
2-(chloromethyl)-6-nitro-4H-benzo[d][1,3]oxazin-4-one
2-(chloromethyl)-6-nitro-3-phenylquinazolin-4(3H)-one
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