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942437-37-8

Q: What is the 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl-?

3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl- is , while it's Molecular Formula is C 19 H 19 FN 4 O 2 . Used in Pharmaceutical Research and Development: 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylis used as a compound for drug design and discovery due to its distinctive molecular structure and potential biological activity. It can be further studied to understand structure-activity relationships in medicinal chemistry, which may lead to the development of new therapeutic agents. Used in Medicinal Chemistry: In the field of medicinal chemistry, 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylis used for investigating the relationship between its molecular structure and its biological activity. This can provide insights into the design of more effective drugs and contribute to the advancement of pharmaceutical science.

Q: What is the CAS number for 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl-?

The CAS number of 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl- is 942437-37-8.

Q: What is 3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl- (942437-37-8) used for?

3-Cinnolinecarboxamide, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylis a chemical compound characterized by a cinnolinecarboxamide backbone, with an amino group at the 4th position and a propyl group at the 8th position. It also features a fluoro group at the 2nd position and a methoxy group at the 6th position of the phenyl group. This unique structure may confer potential biological activity, making it a candidate for pharmaceutical research and development.

Product Name:3-CinnolinecarboxaMide, 4-aMino-8-(2-fluoro-6-Methoxyphenyl)-N-propyl-
Molecular Formula:C19H19FN4O2
Molecular Weight:354.384

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Product Details

Purity:99%

Buy high quality and low price 3-CinnolinecarboxaMide, 4-aMino-8-(2-fluoro-6-Methoxyphenyl)-N-propyl- 942437-37-8 now

Molecular Formula:C₁₉H₁₉FN₄O₂
Molecular Weight:354.384
PSA：90.13000
LogP:4.13860

942437-37-8 Relevant articles

Development and SAR of functionally selective allosteric modulators of GABAA receptors

Alhambra, Cristobal,Becker, Chris,Blake, Timothy,Chang, Amy,Damewood Jr., James R.,Daniels, Thalia,Dembofsky, Bruce T.,Gurley, David A.,Hall, James E.,Herzog, Keith J.,Horchler, Carey L.,Ohnmacht, Cyrus J.,Schmiesing, Richard Jon,Dudley, Adam,Ribadeneira, Maria D.,Knappenberger, Katherine S.,MacIag, Carla,Stein, Mark M.,Chopra, Maninder,Liu, Xiaodong F.,Christian, Edward P.,Arriza, Jeffrey L.,Chapdelaine, Marc J.

experimental part, p. 2927 - 2938 (2011/06/21)

Positive modulators at the benzodiazepin...

Compounds and Uses Thereof - 849

-

, (2009/01/24)

This invention relates to the use of com...

Compounds and Uses Thereof

-

Page/Page column 96-97, (2008/06/13)

This invention relates to novel compound...

942437-37-8 Process route

: 107346-32-7
4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide

: 78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid

: 942437-37-8
AZD7325

Conditions

Conditions	Yield
With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; water; isopropyl alcohol; at 20 - 80 ℃; for 1.75h; Product distribution / selectivity;	88%
With caesium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,2-dimethoxyethane; ethanol; water; at 20 - 150 ℃; for 0.5 - 1.5h; Product distribution / selectivity; Microwave irradiation;	42%
	42%
With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 90 ℃;

: 107346-32-7
4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide

Pd(dppf)Cl_2.CH₂Cl₂: Pd(dppf)Cl_2.CH₂Cl₂

: 7440-44-0
pyrographite

: 78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid

: 942437-37-8
AZD7325

Conditions

Conditions	Yield
With sodium carbonate; In tetrahydrofuran; ethanol; dichloromethane; water; ethyl acetate; isopropyl alcohol;

942437-37-8 Upstream products

107346-32-7
4-amino-8-bromo-N-propyl-cinnoline-3-carboxamide
78495-63-3
(2-fluoro-6-methoxyphenyl)boronic acid
7440-44-0
pyrographite
1253049-53-4
(E)-N-propyl-2-cyano-2-[(2-bromophenyl)hydrazono]acetamide

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