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1421373-66-1

  • Product Name:Osimertinib mesylate
  • Molecular Formula:C29H37N7O5S
  • Molecular Weight:595.723
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Product Details

Purity:99%

Quality manufacturer supply Osimertinib mesylate 1421373-66-1 in stock with high standard We supply high quality AZD-9291 (Mesylate) (CAS 1421373-66-1), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the AZD-9291 (Mesylate) ?

AZD-9291 (Mesylate) is , while it's Molecular Formula is C28H33N7O2.CH4O3S. AZD-9291 Mesylate is a potent and selective epidermal growth factor receptor (EGFR) inhibitor.

What is the CAS number for AZD-9291 (Mesylate) ?

The CAS number of AZD-9291 (Mesylate) is 1421373-66-1.

More information of AZD-9291 (Mesylate) 1421373-66-1 are:

Synonyms

 AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib mesylate;Mereletinib mesylate;Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291)

CAS Number

 1421373-66-1

Molecular Formula

 C28H33N7O2.CH4O3S

Molecular Weight

 595.723

HS CODE

 29339900

PSA

 153.79000

LogP

 5.81710

What is AZD-9291 (Mesylate) (1421373-66-1) used for?

Osimertinib is active against exon 19 deletions, exon 21 mutations, and also the exon 20 T790M mutations. It is preferentially selective for mutated EGFR, and therefore toxicity at therapeutic doses is lower than for first- and second-generation agents. Notably, osimertinib is able to cross the blood-brain barrier, making it active against disease in the CNS.

Articles related to AZD-9291 (Mesylate):

Article

Source

AN IMPROVED PROCESS FOR THE PREPARATION OF OSIMERTINIB MESYLATE

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Paragraph 6; 7, (2021/06/11)

Synthetic method of osimertinib AZD9291

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Paragraph 0075-0081, (2019/01/23)

How to get the best price on AZD-9291 (Mesylate)?

Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier and manufacturer of AZD-9291 (Mesylate) . You can buy high quality, low price AZD-9291 (Mesylate) 1421373-66-1 here. Contact us.

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