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180916-16-9

  • Product Name:Lasofoxifene
  • Molecular Formula:C28H31NO2
  • Molecular Weight:413.56
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Product Details

pd_meltingpoint:110-113°C

Purity:99%

Chinese Factory Supply Wholesale Lasofoxifene 180916-16-9 with Cheap Price

  • Molecular Formula:C28H31NO2
  • Molecular Weight:413.56
  • Vapor Pressure:1.05E-13mmHg at 25°C 
  • Melting Point:110-113°C 
  • Refractive Index:1.613 
  • Boiling Point:572.4 °C at 760 mmHg 
  • PKA:10.31±0.60(Predicted) 
  • Flash Point:300 °C 
  • PSA:32.70000 
  • Density:1.15 g/cm3 
  • LogP:5.66660 

Lasofoxifene(Cas 180916-16-9) Usage

InChI:InChI=1/C28H31NO2/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2/t26-,28+/m1/s1

180916-16-9 Relevant articles

LASOFOXIFENE MODULATION OF MEMBRANE-INITIATED ESTROGEN SIGNALS AND METHODS FOR TUMOR TREATMENT

-

, (2018/08/03)

The present invention found that lasofox...

Total synthesis of lasofoxifene and nafoxidine

Umareddy, Pailla,Arava, Veera Reddy

supporting information, p. 309 - 313 (2016/04/05)

An intramolecular reductive coupling pro...

PROCESS FOR PRODUCTION OF LASOFOXIFENE OR ANALOGUE THEREOF

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Page/Page column 21-22; 30, (2008/12/04)

Disclosed is a novel process for product...

Pharmaceutical composition having uniform drug distribution and potency

-

, (2008/06/13)

Pharmaceutical compositions having unifo...

180916-16-9 Process route

lasofoxifene
180915-78-0

lasofoxifene

lasofoxifene
180916-16-9,180915-78-0

lasofoxifene

Conditions
Conditions Yield
Butyric acid (5S,6R)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester

Butyric acid (5S,6R)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester

(5S,6R)-6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-ol
180915-78-0

(5S,6R)-6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-ol

lasofoxifene
180916-16-9,180915-78-0

lasofoxifene

Butyric acid (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester

Butyric acid (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester

Conditions
Conditions Yield
With Lipase (Mucor Miehei); In phosphate buffer; at 20 ℃; pH=7;

180916-16-9 Upstream products

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    180915-78-0

    lasofoxifene

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    1845-11-0

    nafoxidine

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    1081-73-8

    1-[2-(4-bromophenoxy)ethyl]pyrrolidine

  • 1078-19-9
    1078-19-9

    6-methoxy-3,4-dihydro-1(2H)-naphthalenone

180916-16-9 Downstream products

  • 5879-98-1
    5879-98-1

    1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine

  • 190791-29-8
    190791-29-8

    Lasofoxifene tartrate

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