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pd_meltingpoint:110-113°C
Purity:99%
InChI:InChI=1/C28H31NO2/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2/t26-,28+/m1/s1
The present invention found that lasofox...
An intramolecular reductive coupling pro...
Disclosed is a novel process for product...
Pharmaceutical compositions having unifo...
lasofoxifene
lasofoxifene
| Conditions | Yield |
|---|---|
|
|
Butyric acid (5S,6R)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester
(5S,6R)-6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-ol
lasofoxifene
Butyric acid (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-yl ester
| Conditions | Yield |
|---|---|
|
With
Lipase (Mucor Miehei);
In
phosphate buffer;
at 20 ℃;
pH=7;
|
lasofoxifene
nafoxidine
1-[2-(4-bromophenoxy)ethyl]pyrrolidine
6-methoxy-3,4-dihydro-1(2H)-naphthalenone
1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine
Lasofoxifene tartrate
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