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Purity:99%
It is to provide an agent for preventing...
PROBLEM TO BE SOLVED: To provide a compo...
The present invention provides an erythr...
indole
trans-4-(2,4-difluorophenyl)-4-oxo-2-butenoic acid
4-(2,4-difluorophenyl)-2-(1H-indol-3-yl)-4-oxo-butanoic acid
| Conditions | Yield |
|---|---|
|
In
benzene;
at 80 ℃;
for 8h;
|
51% |
|
In
benzene;
at 80 ℃;
for 8h;
Inert atmosphere;
|
51% |
1,3-Difluorobenzene
4-(2,4-difluorophenyl)-2-(1H-indol-3-yl)-4-oxo-butanoic acid
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: aluminum (III) chloride / dichloromethane / 4 h / 20 °C / Inert atmosphere
2: benzene / 8 h / 80 °C
With
aluminum (III) chloride;
In
dichloromethane; benzene;
|
|
|
Multi-step reaction with 2 steps
1: aluminum (III) chloride / dichloromethane / 4 h / 20 °C / Inert atmosphere
2: benzene / 8 h / 80 °C / Inert atmosphere
With
aluminum (III) chloride;
In
dichloromethane; benzene;
|
indole
trans-4-(2,4-difluorophenyl)-4-oxo-2-butenoic acid
1,3-Difluorobenzene
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