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Purity:99%
InChI:InChI=1/C31H40N4O8/c1-30(2,3)42-28(39)34-26(35-29(40)43-31(4,5)6)32-17-11-16-24(25(36)37)33-27(38)41-18-23-21-14-9-7-12-19(21)20-13-8-10-15-22(20)23/h7-10,12-15,23-24H,11,16-18H2,1-6H3,(H,33,38)(H,36,37)(H2,32,34,35,39,40)/t24-/m0/s1
Here, we applied and optimized a solid s...
The arginine derivative Fmoc-Arg omega;ω...
The natural product miraziridine A isola...
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Nα-benzyloxycarbonyl-L-ornithine
Fmoc-Argω,ω'(Boc)2-OH
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 3 steps
1: Triton-B / methanol; dimethylsulfoxide / 40 h / 10 °C
2: 99 percent / hydrogen / 10percent Pd/C / methanol / 0.67 h / 1551.4 Torr
3: 99.6 percent / DIPEA / CH2Cl2 / 1.17 h
With
hydrogen; N-benzyl-trimethylammonium hydroxide; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
methanol; dichloromethane; dimethyl sulfoxide;
|
9-fluorenylmethyl N-succinimidyl carbonate
H-L-Arg(Boc)2-OH
N-α-(9-fluorenylmethyloxycarbonyl)-N-ω′,N-ω″-bis-tert-butyloxycarbonyl-L-argine
| Conditions | Yield |
|---|---|
|
With
ethylenediaminetetraacetic acid; sodium hydrogencarbonate;
In
acetone;
at 20 ℃;
|
84% |
9-fluorenylmethyl N-succinimidyl carbonate
H-Argω,ω'(Boc)2-OH
Nα-benzyloxycarbonyl-L-ornithine
1,3-bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea
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