What is the 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide?

4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is , while it's Molecular Formula is C16H11ClN2O5S. Used in Pharmaceutical Industry: 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is used as a DNMT1 inhibitor for its potential role in the development of therapeutic agents targeting epigenetic modifications. Its selectivity for human DNMT1 and its inhibitory effects on tumor cell growth make it a promising candidate for cancer treatment and research into the epigenetic regulation of diseases. Used in Cancer Research: In cancer research, 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is utilized to study the role of DNMT1 in the growth and progression of various types of cancer. By inhibiting DNMT1, researchers can investigate the effects on tumor cell growth and genomic methylation, which may lead to the discovery of new treatment strategies and a better understanding of cancer biology. Used in Epigenetic Studies: 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is also used in epigenetic studies to explore the mechanisms of gene regulation and the impact of DNA methylation on gene expression. Its ability to inhibit genomic methylation in HeLa cells provides a valuable tool for researchers to manipulate and study the epigenetic landscape of cells and its implications in various biological processes and diseases.

What is the CAS number for 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide?

The CAS number of 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is 420092-79-1.

What is 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (420092-79-1) used for?

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.

What is the 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide?

4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is , while it's Molecular Formula is C16H11ClN2O5S. Used in Pharmaceutical Industry: 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is used as a DNMT1 inhibitor for its potential role in the development of therapeutic agents targeting epigenetic modifications. Its selectivity for human DNMT1 and its inhibitory effects on tumor cell growth make it a promising candidate for cancer treatment and research into the epigenetic regulation of diseases. Used in Cancer Research: In cancer research, 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is utilized to study the role of DNMT1 in the growth and progression of various types of cancer. By inhibiting DNMT1, researchers can investigate the effects on tumor cell growth and genomic methylation, which may lead to the discovery of new treatment strategies and a better understanding of cancer biology. Used in Epigenetic Studies: 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is also used in epigenetic studies to explore the mechanisms of gene regulation and the impact of DNA methylation on gene expression. Its ability to inhibit genomic methylation in HeLa cells provides a valuable tool for researchers to manipulate and study the epigenetic landscape of cells and its implications in various biological processes and diseases.

What is the CAS number for 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide?

The CAS number of 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide is 420092-79-1.

What is 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (420092-79-1) used for?

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.

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Product Name:SW155246
Molecular Formula:C16H11ClN2O5S
Molecular Weight:378.8

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Purity:99%

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Molecular Formula:C16H11ClN2O5S
Molecular Weight:378.8

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