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Purity:99%
New conjunctive β-silylated organometall...
The reaction of ω-Me3Si- or ω-Me3Ge-subs...
1,1- or n,n-Bismetallic reagents bearing...
Reaction of alkyl 2-alkynoates with sodi...
3-trimethylsilyl-2-propyn-1-ol
(Z)-(3)-(trimethylsilyl)-3-iodo-2-propen-1-ol
| Conditions | Yield |
|---|---|
|
3-trimethylsilyl-2-propyn-1-ol;
With
sodium bis(2-methoxyethoxy)aluminium dihydride;
In
diethyl ether; toluene;
at 0 - 25 ℃;
for 1h;
Inert atmosphere;
With
iodine;
In
tetrahydrofuran; diethyl ether; toluene;
at -40 - 25 ℃;
Inert atmosphere;
|
60% |
|
With
lithium aluminium tetrahydride; iodine; sodium methylate;
In
tetrahydrofuran;
|
|
|
With
iodine; sodium bis(2-methoxyethoxy)aluminium dihydride;
Yield given. Multistep reaction;
1) Et2O, 0 deg C 2) -78 to 23 deg C, 1h;
|
|
|
With
iodine; sodium bis(2-methoxyethoxy)aluminium dihydride;
Yield given. Multistep reaction;
1.) toluene, Et2O, 0 deg C, 10 min, 2.) toluene, EtO2, -78 deg C to room temperature;
|
|
|
With
iodine; sodium bis(2-methoxyethoxy)aluminium dihydride;
|
|
|
With
iodine; sodium bis(2-methoxyethoxy)aluminium dihydride;
Yield given. Multistep reaction;
1.) Et2O, toluene, 0 deg C, 1 h; r.t., 30 min, 2.) r.t., 30 min;
|
|
|
With
iodine; trimethylaluminum; diisobutylaluminium hydride;
Yield given. Multistep reaction;
1.) CH2Cl2, 23 deg C, 30 min, 2.) CH2Cl2, 23 deg C, 24 h, 3.) CH2Cl2, THF, -78 deg C;
|
ethyl (Z)-3-iodo-3-(trimethylsilyl)propenoate
(Z)-(3)-(trimethylsilyl)-3-iodo-2-propen-1-ol
| Conditions | Yield |
|---|---|
|
With
diisobutylaluminium hydride;
In
diethyl ether; hexane;
1.) -78 deg C, 75 min, 2.) 0 deg C, 95 min;
|
75% |
3-trimethylsilyl-2-propyn-1-ol
ethyl (Z)-3-iodo-3-(trimethylsilyl)propenoate
ethyl 3-(trimethylsilyl)propynoate
((E)-3-chloro-1-methylpropenyl)trimethylsilane
(E)-(3-iodo-1-methyl-1-propenyl)-trimethylsilane
(Z)-N,N-diethyl-2-phenyl-5-iodo-5-(trimethylsilyl)-4-pentenamide
5-Phenyl-2-trimethylsilanyl-cyclopent-2-enone
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