Your Location:Home >Products >small-molecule inhibitor >2239273-34-6
Purity:99%
AB928 is a potent and selective dual ant...
The present invention provides solid for...
Provided herein are improved processes f...
Provided herein are methods of treating ...
2-(6-(azidomethyl)pyridin-2-yl)propan-2-ol
3-(2-amino-6-ethynylpyrimidin-4-yl)-2-methylbenzonitrile
3-(2-amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile
Conditions | Yield |
---|---|
With
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
water; tert-butyl alcohol;
at 60 ℃;
for 13h;
|
90% |
With
copper(II) sulfate; sodium L-ascorbate;
In
water; tert-butyl alcohol;
at 60 ℃;
for 13h;
|
90% |
With
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
In
water; tert-butyl alcohol;
at 60 ℃;
for 13h;
|
90% |
With
copper(ll) sulfate pentahydrate; sodium L-ascorbate;
|
90% |
With
copper(I) sulfate pentahydrate; sodium L-ascorbate;
In
tetrahydrofuran; tert-butyl methyl ether; water;
at 60 ℃;
for 20h;
Solvent;
Temperature;
|
3-(2-amino-6-{2-[tris(propan-2-yl)silyl]ethynyl}-pyrimidin-4-yl)-2-methylbenzonitrile
3-(2-amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C
2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 13 h / 60 °C
With
copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; sodium L-ascorbate;
In
tetrahydrofuran; water; tert-butyl alcohol;
|
|
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C
2: copper(II) sulfate; sodium L-ascorbate / water; tert-butyl alcohol / 13 h / 60 °C
With
tetrabutyl ammonium fluoride; copper(II) sulfate; sodium L-ascorbate;
In
tetrahydrofuran; water; tert-butyl alcohol;
|
|
Multi-step reaction with 2 steps
1: tetra(n-butyl)ammonium hydroxide / tetrahydrofuran / 0.5 h / 0 - 20 °C
2: sodium L-ascorbate; copper(I) sulfate pentahydrate / water; tetrahydrofuran; tert-butyl methyl ether / 20 h / 60 °C
With
copper(I) sulfate pentahydrate; tetra(n-butyl)ammonium hydroxide; sodium L-ascorbate;
In
tetrahydrofuran; tert-butyl methyl ether; water;
|
|
Multi-step reaction with 2 steps
1: dipotassium hydrogenphosphate; tetra(n-butyl)ammonium hydroxide / water; tetrahydrofuran / 1.5 h / 20 °C
2: sodium L-ascorbate; copper(I) sulfate pentahydrate / water; tetrahydrofuran; tert-butyl methyl ether / 20 h / 60 °C
With
dipotassium hydrogenphosphate; copper(I) sulfate pentahydrate; tetra(n-butyl)ammonium hydroxide; sodium L-ascorbate;
In
tetrahydrofuran; tert-butyl methyl ether; water;
|
2-(6-(azidomethyl)pyridin-2-yl)propan-2-ol
2-hydroxymethyl-6-(1-hydroxy-1-methylethyl)pyridine
methyl 6-(hydroxymethyl)pyridine-2-carboxylate
2-methyl-3-cyano-benzoic acid
CAS:68592-15-4
CAS:147-94-4
CAS:9002-01-1
CAS:1505514-27-1