What is the 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione?

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is , while it's Molecular Formula is C 19 H 14 N 2 O 2 S. Tideglusib has been used:as a reference compound in ADP-GloTM Kinase assayas an allosteric inhibitor of GSK-3β to study its effects on myocardial remodeling and angiogenesis as a differentiation agent (specifically a glycogen synthase kinase (GSK)-3β inhibitor) to convert fibroblast cells into octamer-binding transcription factor-4 (OCT4)+ and vascular endothelial growth factor receptor-2 (VEGFR-2/fetal liver kinase-1 (FLK1)+ cells

What is the CAS number for 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione?

The CAS number of 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is 865854-05-3.

What is 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione (865854-05-3) used for?

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is a complex organic compound with a unique molecular structure that features a benzyl group, a naphthalen-1-yl group, and a [1,2,4]thiadiazolidine-3,5-dione moiety. 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione has potential applications in various fields due to its distinct chemical properties.

What is the 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione?

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is , while it's Molecular Formula is C 19 H 14 N 2 O 2 S. Tideglusib has been used:as a reference compound in ADP-GloTM Kinase assayas an allosteric inhibitor of GSK-3β to study its effects on myocardial remodeling and angiogenesis as a differentiation agent (specifically a glycogen synthase kinase (GSK)-3β inhibitor) to convert fibroblast cells into octamer-binding transcription factor-4 (OCT4)+ and vascular endothelial growth factor receptor-2 (VEGFR-2/fetal liver kinase-1 (FLK1)+ cells

What is the CAS number for 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione?

The CAS number of 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is 865854-05-3.

What is 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione (865854-05-3) used for?

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione is a complex organic compound with a unique molecular structure that features a benzyl group, a naphthalen-1-yl group, and a [1,2,4]thiadiazolidine-3,5-dione moiety. 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione has potential applications in various fields due to its distinct chemical properties.

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865854-05-3

Product Name:Tideglusib
Molecular Formula:C19H14N2O2S
Molecular Weight:334.398

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Product Details

Purity:99%

Quality Factory Supply 99% Pure Tideglusib 865854-05-3 with Efficient Delivery

Molecular Formula:C₁₉H₁₄N₂O₂S
Molecular Weight:334.398
Boiling Point:511.3±43.0 °C(Predicted)
PKA:-1.51±0.20(Predicted)
PSA：72.24000
Density:1.393
LogP:3.26220

865854-05-3 Relevant articles

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GSK-3 inhibitors

-

Page/Page column 7-8, (2008/06/13)

Provided are thiadiazolidine compounds o...

Thiadiazolidinones as GSK-3 inhibitors

-

Page/Page column 8, (2008/06/13)

Provided are compounds of formula I wher...

865854-05-3 Process route

: C₁₉H₁₄Cl₂N₂OS

: 865854-05-3
Tideglusib

Conditions

Conditions	Yield
With air; In tetrahydrofuran; for 0.5h;

: 622-78-6
Benzyl isothiocyanate

: 86-84-0
1-Naphthyl isocyanate

: 865854-05-3
Tideglusib

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: thionyl chloride / tetrahydrofuran / 0 - 20 °C 2: air / tetrahydrofuran / 0.5 h With thionyl chloride; In tetrahydrofuran;

865854-05-3 Upstream products

622-78-6
Benzyl isothiocyanate
86-84-0
1-Naphthyl isocyanate

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