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pd_meltingpoint:228 °C (decomp)(Solv: ethyl acetate (141-78-6); tetrahydrofuran (109-99-9))
Purity:99%
Manufacturer supply top purity Relugolix 737789-87-6 with GMP standards We supply high quality TAK-385 (CAS 737789-87-6), in stock, factory directly supply to clients, lower prices, more competitiveness.
TAK-385 is , while it's Molecular Formula is C29H27F2N7O5S. Relugolix is a highly selective, oral, nonpeptide GnRH antagonist being investigated as a possible prostate cancer treatment
The CAS number of TAK-385 is 737789-87-6.
More information of TAK-385 737789-87-6 are:
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Synonyms |
1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea;TAK-385; |
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CAS Number |
737789-87-6 |
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Molecular Formula |
C29H27F2N7O5S |
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Molecular Weight |
623.63 |
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Density |
1.442±0.06 g/cm3(Predicted) |
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Melting Point |
228 °C (decomp)(Solv: ethyl acetate (141-78-6); tetrahydrofuran (109-99-9)) |
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PSA |
182.86000 |
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LogP |
3.69890 |
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Pka |
13.17±0.70(Predicted) |
Relugolix (TAK-385)?is a potent, orally active, nonpeptidic?gonadotropin-releasing hormone (GnRH)?antagonist. It possesses high affinity and potent antagonistic activity for human receptor (binding?IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209). Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al.
Articles related to TAK-385:
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Article |
Source |
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Preparation method of Rurugolix |
- , (2022/03/31) |
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Preparation method of Relugolix and intermediate compounds |
- Paragraph 0062-0064, (2021/05/05) |
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