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62658-63-3

  • Product Name:Bopindolol
  • Molecular Formula:C23H28N2O3
  • Molecular Weight:380.48
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Product Details

Purity:99%

99% Purity Commercial production Bopindolol 62658-63-3 with Cheapest Price

  • Molecular Formula:C23H28N2O3
  • Molecular Weight:380.48
  • Vapor Pressure:1.92E-12mmHg at 25°C 
  • Refractive Index:1.592 
  • Boiling Point:557 °C at 760 mmHg 
  • PKA:17.59±0.30(Predicted) 
  • Flash Point:290.7 °C 
  • PSA：63.35000 
  • Density:1.143 g/cm3 
  • LogP:4.85970 

2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER)(Cas 62658-63-3) Usage

Manufacturing Process

4-(2-Benzoyloxy-3-t-butylaminopropoxy)-2-methyl-indole: 26 g of benzoic acid are dissolved, while heating, in 50 ml of hexamethylphosphoric acid triamide and 3.5 g of 1-t-butylamino-3-(2-methylindole- 4-yloxy)-2-propanol are added. After cooling, 3.0 g of benzoic acid anhydride are added and stirred for 20 hours at room temperature. The resulting clear, yellow solution is poured onto ice 0.5 liters of ether are added and stirred for 2 hours. After making the liquid alkaline with concentrated ammonia, the ether phase is separated, shaken out with tartaric acid, made alkaline with caustic soda solution while cooling with ice and extracted with methylene chloride. After evaporating the solvent, the residue is crystallized with 1 mol of fumaric acid from methanol and acetone.

Therapeutic Function

Beta-adrenergic blocker

Brand name

SANDONORM

InChI:InChI=1/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23(2,3)4)28-22(26)17-9-6-5-7-10-17/h5-13,18,24-25H,14-15H2,1-4H3

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