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98809-69-9

  • Product Name:6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline
  • Molecular Weight:269.343
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Product Details

Purity:99%

Manufacturer supply top purity 6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline 98809-69-9 with GMP standards

  • Molecular Formula:C17H19NO2
  • Molecular Weight:269.343

98809-69-9 Relevant articles

RHODIUM CATALYZED HYDROGENATION OF NITROGEN HETEROAROMATICS UNDER WATER GAS SHIFT CONDITIONS. SELECTIVE SYNTHESIS OF 1,2,3,4-TETRAHYDROQUINOLINES AND N-FORMYL-1,2,3,4-TETRAHYDROISOQUINOLINES

Murahashi, Shun-Ichi,Imada, Yasushi,Hirai, Yoshiaki

, p. 77 - 80 (1987)

Quinolines and isoquinolines are hydroge...

NOVEL ANTHRANILIC ACID DERIVATIVES

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Paragraph 000119, (2016/07/20)

The present invention is directed to a n...

Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors

Leese, Mathew P.,Jourdan, Fabrice L.,Major, Meriel R.,Dohle, Wolfgang,Hamel, Ernest,Ferrandis, Eric,Fiore, Ann,Kasprzyk, Philip G.,Potter, Barry V. L.

, p. 85 - 108 (2014/01/17)

A structure-activity relationship (SAR) ...

Steroidomimetic tetrahydroisoquinolines for the design of new microtubule disruptors

Leese, Mathew P.,Jourdan, Fabrice,Dohle, Wolfgang,Kimberley, Meriel R.,Thomas, Mark P.,Bai, Ruoli,Hamel, Ernest,Ferrandis, Eric,Potter, Barry V. L.

scheme or table, p. 5 - 9 (2012/04/04)

Structure-activity relationship translat...

Chimeric microtubule disruptors

Leese, Mathew P.,Jourdan, Fabrice,Kimberley, Meriel R.,Cozier, Gyles E.,Thiyagarajan, Nethaji,Stengel, Chloe,Regis-Lydi, Sandra,Foster, Paul A.,Newman, Simon P.,Acharya, K. Ravi,Ferrandis, Eric,Purohit, Atul,Reed, Michael J.,Potter, Barry V. L.

supporting information; experimental part, p. 2907 - 2909 (2010/08/04)

A chimeric approach is used to discover ...

98809-69-9 Process route

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

3-benzyloxy-4-methoxyphenylethylamine
36455-21-7

3-benzyloxy-4-methoxyphenylethylamine

6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline
98809-69-9

6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline

Conditions
Conditions Yield
With formic acid; at 40 ℃; for 24h;
84%
With formic acid; for 12h; Heating;
With lithium aluminium tetrahydride; In formic acid; at 40 - 45 ℃; for 4h;
78 g
N-acetyl-1,2,3,4-tetrahydroisoquinoline
124066-12-2

N-acetyl-1,2,3,4-tetrahydroisoquinoline

6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline
98809-69-9

6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline

Conditions
Conditions Yield
With sodium hydroxide; In ethanol; water; at 120 ℃; for 16h;
94%
With water; potassium hydroxide; In ethanol; Reflux;

98809-69-9 Upstream products

  • 50-00-0
    50-00-0

    formaldehyd

  • 36455-21-7
    36455-21-7

    3-benzyloxy-4-methoxyphenylethylamine

  • 109849-38-9
    109849-38-9

    N-formyl-6-benzyloxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline

  • 63909-29-5
    63909-29-5

    3-benzyloxy-4-methoxy-β-nitrostyrene

98809-69-9 Downstream products

  • 911057-03-9
    911057-03-9

    adamantan-1-yl-(6-benzyloxy-7-methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-methanone

  • 1064201-17-7
    1064201-17-7

    6-benzyloxy-7-methoxy-2-(3-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline

  • 1064206-84-3
    1064206-84-3

    6-benzyloxy-7-methoxy-2-(2,4,6-trimethoxybenzoyl)-1,2,3 ,4-tetrahydroisoquinoline

  • 1064198-42-0
    1064198-42-0

    6-hydroxy-7-methoxy-2-(3-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

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