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872511-34-7

  • Product Name:Infigratinib
  • Molecular Formula:C26H31Cl2N7O3
  • Molecular Weight:560.483
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Product Details

Purity:99%

Manufacturer Sells Best Quality Infigratinib 872511-34-7 with stock

  • Molecular Formula:C26H31Cl2N7O3
  • Molecular Weight:560.483
  • Boiling Point:747.9±60.0 °C(Predicted) 
  • PKA:11.02±0.70(Predicted) 
  • PSA：95.09000 
  • Density:1.354 
  • LogP:5.50330 

3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea(Cas 872511-34-7) Usage

InChI:InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)

872511-34-7 Relevant articles

CRYSTALLINE FORMS OF 3-(2,6-DICHLORO-3,5-DIMETHOXY-PHENYL)-1-{6-[4-(4-ETHYL-PIPERAZIN-1-YL)-PHENYLAMINO]-PYRIMIDIN-4-YL}-1-METHYL-UREA AND SALTS THEREOF.

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Page/Page column 22, (2011/06/26)

The present technology provides novel an...

PYRIMIDINE UREA DERIVATIVES AS KINASE INHIBITORS

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Page/Page column 209, (2008/06/13)

The invention relates to compounds of fo...

872511-34-7 Process route

NVP-BGJ<sub>398</sub> phosphoric acid
1310746-10-1

NVP-BGJ398 phosphoric acid

NVP-BGJ398
872511-34-7

NVP-BGJ398

Conditions
Conditions Yield
With ammonium hydroxide; at 18 ℃; for 17h; Inert atmosphere;
96.7%
2,4-dichloro-3-isocyanato-1,5-methoxy-4-methylbenzene
872511-32-5

2,4-dichloro-3-isocyanato-1,5-methoxy-4-methylbenzene

of N<SUP>4</SUP>-(4-(4-ethylpiperazin-1-yl)phenyl)-N<SUP>6</SUP>-methylpyrimidine-4,6-diamine
872511-35-8

of N4-(4-(4-ethylpiperazin-1-yl)phenyl)-N6-methylpyrimidine-4,6-diamine

NVP-BGJ398
872511-34-7

NVP-BGJ398

Conditions
Conditions Yield
In toluene; for 1.5h; Reflux;
 

872511-34-7 Upstream products

  • 872511-32-5
    872511-32-5

    2,4-dichloro-3-isocyanato-1,5-methoxy-4-methylbenzene

  • 872511-35-8
    872511-35-8

    of N4-(4-(4-ethylpiperazin-1-yl)phenyl)-N6-methylpyrimidine-4,6-diamine

  • 1310746-10-1
    1310746-10-1

    NVP-BGJ398 phosphoric acid

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