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10212-20-1

Q: What is the CAS number for 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one?

The CAS number of 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one is 10212-20-1.

Product Name:4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Molecular Formula:C₉H₁₂FN₃O₄
Molecular Weight:245.21
Appearance:White or almost white crystalline powder

Inquiry

Product Details

pd_meltingpoint:167 °C

Appearance:White or almost white crystalline powder

Purity:99%

Reliable factory customized supply 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 10212-20-1

Molecular Formula:C9H12FN3O4
Molecular Weight:245.21
Appearance/Colour:White or almost white crystalline powder
Melting Point:167 °C
Refractive Index:80 ° (C=1, MeOH)
Boiling Point:500.1 °C at 760 mmHg
PKA:12.84±0.70(Predicted)
Flash Point:256.2 °C
PSA：110.60000
Density:1.82 g/cm³
LogP:-1.00460

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one(Cas 10212-20-1) Usage

InChI:InChI=1/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6?,7-,8-/m1/s1

10212-20-1 Relevant articles

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Based on the discovery of β-D-2′-deoxy-2...

10212-20-1 Process route

: 56287-17-3,69123-94-0,784-71-4
2'-deoxy-2'-fluorouridine

: 10212-20-1
2'-deoxy-2'-fluorocytidine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 92 percent / pyridine / 2 h / Ambient temperature 2: (PhO)2POCl, Et₃N / acetonitrile / 1.5 h / Ambient temperature 3: 32percent aq. NH₃ / dioxane / 0.33 h 4: EtNMe₂ / methanol / 24 h / 50 °C With ammonium hydroxide; N,N-dimethyl-ethanamine; triethylamine; chlorophosphoric acid diphenyl ester; In 1,4-dioxane; pyridine; methanol; acetonitrile;

: 3',5'-Di-O-benzoyl-2'-desoxy-2'-fluorcytidin

: 10212-20-1
2'-deoxy-2'-fluorocytidine

Conditions

Conditions	Yield
With ammonium hydroxide; at 50 ℃;	56%

10212-20-1 Upstream products

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9-<2-deoxy-2-fluoro-3,5-di-O-(tetrahydropyran-2-yl)-β-D-ribofuranosyl>cytosine
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cyclocitidine
10212-13-2
3’,5’-O-acetyl-2’-deoxy-2’-fluorouridine
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2'-deoxy-2'-fluorouridine

10212-20-1 Downstream products

146954-76-9
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134444-47-6
2,6-diamino-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-9H-purine
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5-iodo-2'-deoxy-2'-(R)-fluoro-cytidine
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2'-deoxy-2'-fluoroguanosine

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