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4277-34-3

  • Product Name:Cyclooct-4-en-1-ol
  • Molecular Formula:C8H14O
  • Molecular Weight:126.199
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Product Details

Purity:99%

Cost-effective and customizable Cyclooct-4-en-1-ol 4277-34-3 supplier

  • Molecular Formula:C8H14O
  • Molecular Weight:126.199
  • Vapor Pressure:0.0724mmHg at 25°C 
  • Boiling Point:202.2°Cat760mmHg 
  • PKA:15.13±0.20(Predicted) 
  • Flash Point:75.6°C 
  • PSA:20.23000 
  • Density:0.954g/cm3 
  • LogP:1.86760 

cyclooct-4-en-1-ol(Cas 4277-34-3) Usage

General Description

Cyclooct-4-en-1-ol is a chemical compound known for its strong woody, minty, herbal, and camphoraceous odor. This chemical, characterized by a cyclooctene backbone with a hydroxyl group (-OH) at its first carbon and a double bond between its fourth and fifth carbons, primarily functions in creating scents and flavors in product manufacturing. It is considerably utilized in the flavoring and fragrance industry due to its unique aromatic features. However, like any other chemical substance, it may pose risks and hazards when mishandled or used inappropriately. Thus, safety measures, including wearing personal protective types of equipment, should be observed when handling cyclooct-4-en-1-ol.

InChI:InChI=1/C8H14O/c9-8-6-4-2-1-3-5-7-8/h1-2,8-9H,3-7H2/b2-1-

4277-34-3 Relevant articles

A Simple, Readily Accessible, and Effective Apparatus for the Photoisomerization of cis -Cyclooctenes to trans -Cyclooctenes

Pickel, Thomas C.,Genung, Nathan E.,Guckian, Kevin M.,Shi, Xianglin

supporting information, p. 1711 - 1713 (2021/08/10)

A simple, cost effective, and readily ac...

General, Divergent Platform for Diastereoselective Synthesis of trans-Cyclooctenes with High Reactivity and Favorable Physiochemical Properties**

Pigga, Jessica E.,Rosenberger, Julia E.,Jemas, Andrew,Boyd, Samantha J.,Dmitrenko, Olga,Xie, Yixin,Fox, Joseph M.

, p. 14975 - 14980 (2021/05/31)

trans-Cyclooctenes (TCOs) are essential ...

A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates

Baalmann, Mathis,Bitsch, Sebastian,Deweid, Lukas,Ilkenhans, Nadja,Kolmar, Harald,Neises, Laura,Schneider, Hendrik,Werther, Philipp,Wilhelm, Jonas,Wolfring, Martin,Wombacher, Richard,Ziegler, Michael J.

supporting information, p. 12885 - 12893 (2020/06/02)

Bioorthogonal chemistry holds great pote...

Optimization of IEDDA bioorthogonal system: Efficient process to improve trans-cyclooctene/tetrazine interaction

Béquignat, Jean-Baptiste,Boucheix, Claude,Canitrot, Damien,Chezal, Jean-Michel,Degoul, Fran?oise,Miot-Noirault, Elisabeth,Moreau, Emmanuel,Navarro-Teulon, Isabelle,Quintana, Mercedes,Rondon, Aurélie,Taiariol, Ludivine,Ty, Nancy

supporting information, (2020/07/21)

The antibody pretargeting approach for r...

4277-34-3 Process route

cis-1,4-dihydroxycyclooctane
73982-04-4

cis-1,4-dihydroxycyclooctane

cis-Cyclooctene
931-88-4,931-87-3,25267-51-0

cis-Cyclooctene

3-cyclohexenol
4114-99-2

3-cyclohexenol

(Z)-cyclooct-4-enol
4277-34-3

(Z)-cyclooct-4-enol

(E)-cyclooctanol-4-d
79734-94-4

(E)-cyclooctanol-4-d

Conditions
Conditions Yield
With lithium triethyl borodeuteride; p-toluenesulfonyl chloride; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; 1.) pyridine, -5 deg C, 24 h, 2.) THF;
(Z)-9-oxabicyclo[6.1.0]non-4-ene
19740-90-0,57378-34-4,65207-47-8,73176-71-3,73176-86-0,117468-08-3,637-90-1

(Z)-9-oxabicyclo[6.1.0]non-4-ene

(Z)-cyclooct-4-enol
4277-34-3

(Z)-cyclooct-4-enol

Conditions
Conditions Yield
With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 4h;
96.1%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 4h; Reflux;
95%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 4h; Reflux;
95%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 24h;
89%
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;
88%
With ammonia; sodium;
87%
With lithium aluminium tetrahydride; In diethyl ether; for 24h; Heating;
70%
With lithium aluminium tetrahydride; In diethyl ether; Yield given;
With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;
1.03 g
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;
With lithium aluminium tetrahydride; In tetrahydrofuran; at 65 - 70 ℃; for 4h;
(Z)-9-oxabicyclo[6.1.0]non-4-ene; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Reflux;
With water; sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃;

4277-34-3 Upstream products

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    1,5-cis,cis-cyclooctadiene

  • 19740-90-0
    19740-90-0

    (Z)-9-oxabicyclo[6.1.0]non-4-ene

  • 31598-73-9
    31598-73-9

    4-cycloocten-1-yl acetate

  • 73982-04-4
    73982-04-4

    cis-1,4-dihydroxycyclooctane

4277-34-3 Downstream products

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    2-(Phenylseleno)-9-oxabicyclo<3.3.1>nonane

  • 29359-87-3
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    (1S,2S,6S)-9-Oxa-bicyclo[4.2.1]nonan-2-ol

  • 31598-76-2
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    (1S,2S,5R)-9-Oxa-bicyclo[3.3.1]nonan-2-ol

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