pd_meltingpoint:132-135 °C(lit.)
Appearance:purple to brown crystalline powder
Purity:99%
|
Chemical Composition and Structure |
4-Morpholinoaniline, also known as 4-MA, is a compound composed of a morpholine ring attached to an aniline ring. Its chemical structure consists of an amino group attached to the benzene ring of aniline and a morpholine group attached to the same benzene ring. |
|
Mechanism of Action |
The mechanism of action of 4-Morpholinoaniline varies depending on its application. In electrochemical processes, it undergoes oxidation to form quinone-diimine derivatives, which can further react with nucleophiles.[3] In biological systems, such as DNA interaction studies, it may exhibit DNA cleavage activity and cytotoxic/phototoxic properties. |
|
Analysis Method |
Analysis of 4-Morpholinoaniline and its derivatives can be performed using various spectroscopic techniques, such as Fourier Transform–Infrared (FT–IR) spectroscopy, Mass Spectra Analysis (MALDI–TOF–MS), and Nuclear Magnetic Resonance (NMR) spectroscopy. Additionally, its interaction with DNA and cytotoxic/phototoxic properties can be evaluated using assays such as agarose gel electrophoresis and MTT assay. |
InChI:InChI=1/C10H14N2O/c11-9-1-3-10(4-2-9)12-5-7-13-8-6-12/h1-4H,5-8,11H2
The invention discloses I, 2 and 6 polys...
Transition metal catalysis that utilizes...
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The invention relates to a hydroboration...
N-(4-chlorophenyl)morpholine
4-morpholino-4-yl-phenylamine
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide; potassium phosphate; copper(l) iodide; N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide;
In
water; dimethyl sulfoxide;
at 110 ℃;
for 24h;
Inert atmosphere;
|
83% |
|
With
dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate;
In
1,4-dioxane;
at 60 ℃;
for 24h;
Inert atmosphere;
|
80% |
4-bromophenyl-morpholine
4-morpholino-4-yl-phenylamine
| Conditions | Yield |
|---|---|
|
With
copper(I) oxide; ammonium hydroxide; N1-(furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide; potassium hydroxide;
In
ethanol;
at 80 ℃;
for 24h;
Schlenk technique;
Inert atmosphere;
|
91% |
4-(4-nitroso-phenyl)-morpholine
1-morpholino-4-nitrobenzene
morpholine
4-bromo-aniline
N-furfurylidene-4-morpholino-aniline
acetoacetic acid-(4-morpholino-anilide)
2-[(4-Morpholino-phenylimino)-methyl]-phenol
N-(4-morpholinophenylcarbamothioyl)benzamide
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