6531-38-0

  • Product Name:Piperazine-1,4-diethylamine
  • Molecular Formula:C8H20N4
  • Molecular Weight:172.274
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Product Details

pd_meltingpoint:40 °C

Purity:99%

Top Quality Chinese Factory supply 6531-38-0 Piperazine-1,4-diethylamine

  • Molecular Formula:C8H20N4
  • Molecular Weight:172.274
  • Vapor Pressure:0.00101mmHg at 25°C 
  • Melting Point:40 °C 
  • Refractive Index:1.511 
  • Boiling Point:302.2 °C at 760 mmHg 
  • PKA:10.41±0.10(Predicted) 
  • Flash Point:151.4 °C 
  • PSA:58.52000 
  • Density:1.006g/cm3 
  • LogP:-0.20220 

Piperazine-1,4-diethylamine(Cas 6531-38-0) Usage

General Description

Piperazine-1,4-diethylamine, also known as 1,4-bis(2-ethylhexyl)piperazine, is a chemical compound that is often used in the synthesis of other chemicals, including pharmaceutical products. It has a molecular formula of C14H32N2 and it exists in a liquid state at room temperature. Piperazine-1,4-diethylamine is colorless, possesses a mild odor, and is soluble in most organic solvents. It should be handled with care as it is corrosive and can cause significant eye, skin, and respiratory irritation. It may also have harmful effects if swallowed or inhaled.

InChI:InChI=1/C8H20N4/c9-1-3-11-5-7-12(4-2-10)8-6-11/h1-10H2

6531-38-0 Relevant articles

Bis-aminals of linear tetraamines: Kinetic and thermodynamic aspects of the condensation reaction

Chuburu, Francoise,Tripier, Raphael,Le Baccon, Michel,Handel, Henri

, p. 1050 - 1055 (2003)

The kinetic and thermodynamic aspects of...

Metal ion substitution and aldehyde exchange for CuII4 aggregates from two types of piperazine-based Schiff base ligands: Synthesis, X-ray structures, magnetic studies and theoretical validation

Basak, Dipmalya,Ray, Debashis

, (2020)

Two new tetranuclear CuII complexes [Cu4...

Syntheses and crystal structures of Ni(II) complexes with pyridine-based macrocyclic ligands

Císa?ová, Ivana,Draho?, Bohuslav,Zahradníková, Eva

supporting information, (2021/11/17)

Three pyridine-based macrocyclic ligands...

CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE UNCHARGED BISOXIME ANTIDOTES FOR ORGANOPHOSPHATE POISONING AND METHODS FOR MAKING AND USING THEM

-

Page/Page column 38; 41; 45-46, (2020/12/07)

In alternative embodiments, provided are...

The effect of the structure of derivatives of nitrogen-containing heterocycles on their anti-influenza activity

Gridina, Tatyana L.,Fedchuk, Alla S.,Basok, Stephan S.,Artemenko, Anatoliy G.,Ognichenko, Liudmila N.,Shitikova, Larisa I.,Lutsyuk, Anatolii F.,Gruzevskii, Aleksandr A.,Kuz’min, Victor E.

, p. 455 - 462 (2019/06/20)

[Figure not available: see fulltext.] An...

6531-38-0 Process route

2‐[4‐(cyanomethyl)piperazin‐1‐yl]acetonitrile
5623-99-4

2‐[4‐(cyanomethyl)piperazin‐1‐yl]acetonitrile

1,4-bis(2-aminoethyl)piperazine
6531-38-0

1,4-bis(2-aminoethyl)piperazine

Conditions
Conditions Yield
With Raney nickel; In methanol; water;
90%
With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Reflux;
87%
2‐[4‐(cyanomethyl)piperazin‐1‐yl]acetonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Heating / reflux;
With potassium hydroxide; In tetrahydrofuran; water;
80%
With ammonia; hydrogen; nickel; In ethanol; at 20 ℃;
73%
2‐[4‐(cyanomethyl)piperazin‐1‐yl]acetonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 3.25h; Reflux;
With potassium hydroxide; In tetrahydrofuran; pH=8 - 9;
41%
With lithium aluminium tetrahydride; In various solvent(s); for 1h; Heating;
With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 90 ℃; for 4h; Inert atmosphere;
Glyoxal
131543-46-9,107-22-2

Glyoxal

triethylentetramine
112-24-3

triethylentetramine

1,4-bis(2-aminoethyl)piperazine
6531-38-0

1,4-bis(2-aminoethyl)piperazine

Conditions
Conditions Yield
With sodium tetrahydroborate; In ethanol; at -10 ℃; for 2h;
With sodium tetrahydroborate;
With sodium tetrahydroborate; In ethanol; at 0 ℃; for 2h;

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