What is the N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide?

N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is , while it's Molecular Formula is C29H31F3N6O3. WS6 is a β-cell proliferation indocer via the IκB kinase pathway and modulation of the Erb3 binding-protein. Potential treatment and cure for diabetes type I.

What is the CAS number for N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide?

The CAS number of N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is 1421227-53-3.

What is N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide (1421227-53-3) used for?

N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is a complex organic compound with a unique molecular structure. It is characterized by its multiple functional groups, including a cyclopropanecarboxamide moiety, a pyrimidinyl group, and a trifluoromethylphenyl group. N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide has potential applications in various fields due to its structural diversity and functional groups.

What is the N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide?

N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is , while it's Molecular Formula is C29H31F3N6O3. WS6 is a β-cell proliferation indocer via the IκB kinase pathway and modulation of the Erb3 binding-protein. Potential treatment and cure for diabetes type I.

What is the CAS number for N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide?

The CAS number of N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is 1421227-53-3.

What is N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide (1421227-53-3) used for?

N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide is a complex organic compound with a unique molecular structure. It is characterized by its multiple functional groups, including a cyclopropanecarboxamide moiety, a pyrimidinyl group, and a trifluoromethylphenyl group. N-(6-(4-(2-((4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide has potential applications in various fields due to its structural diversity and functional groups.

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1421227-53-3

Product Name:WS6
Molecular Formula:C29H31F3N6O3
Molecular Weight:568.59

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Product Details

Purity:99%

Buy cost-effective 99% pure WS6 1421227-53-3 now

Molecular Formula:C29H31F3N6O3
Molecular Weight:568.59
Boiling Point:744.1±60.0 °C(Predicted)
PKA:11.82±0.20(Predicted)
PSA：99.69000
Density:1.374±0.06 g/cm3(Predicted)
LogP:4.58660

1421227-53-3 Relevant articles

Small-molecule inducer of β cell proliferation identified by high-throughput screening

Shen, Weijun,Tremblay, Matthew S.,Deshmukh, Vishal A.,Wang, Weidong,Filippi, Christophe M.,Harb, George,Zhang, You-Qing,Kamireddy, Anwesh,Baaten, Janine E,Jin, Qihui,Wu, Tom,Swoboda, Jonathan G.,Cho, Charles Y.,Li, Jing,Laffitte, Bryan A.,McNamara, Peter,Glynne, Richard,Wu, Xu,Herman, Ann E.,Schultz, Peter G.

, p. 1669 - 1672 (2013/04/23)

The identification of factors that promo...

1421227-53-3 Process route

: 694499-26-8
4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline

: 1421227-58-8
2-(4-(6-(cyclopropanecarboxamido)pyrimidin-4-yloxy)phenyl)acetic acid

: 1421227-53-3
N-(6-(4-(2-((4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 7h;	52%

: 14199-15-6
Methyl 4-hydroxyphenylacetate

: 1421227-53-3
N-(6-(4-(2-((4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)amino)-2-oxoethyl)phenoxy)pyrimidin-4-yl)cyclopropanecarboxamide

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: potassium carbonate / N,N-dimethyl-formamide / 70 °C 2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; caesium carbonate / 1,4-dioxane / 4 h / 110 °C / Inert atmosphere 3: lithium hydroxide monohydrate; water / methanol; tetrahydrofuran / 0.5 h / 20 °C 4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 7 h / 20 °C With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium hydroxide monohydrate; water; potassium carbonate; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;

Yield

Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 70 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; caesium carbonate / 1,4-dioxane / 4 h / 110 °C / Inert atmosphere

3: lithium hydroxide monohydrate; water / methanol; tetrahydrofuran / 0.5 h / 20 °C

4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 7 h / 20 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; lithium hydroxide monohydrate; water; potassium carbonate; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;

1421227-53-3 Upstream products

14199-15-6
Methyl 4-hydroxyphenylacetate
1246636-79-2
methyl 2-(4-(6-chloropyrimidin-4-yloxy)phenyl)acetate
1421227-57-7
methyl 2-(4-(6-(cyclopropanecarboxamido)pyrimidin-4-yloxy)phenyl)acetate
694499-26-8
4-(4-methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline

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