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pd_meltingpoint:202-203 °C(lit.)
Purity:99%
Cost-effective and customizable (S)-Timolol maleate 26921-17-5 in stock We supply high quality (S)-Timolol maleate (CAS 26921-17-5), in stock, factory directly supply to clients, lower prices, more competitiveness.
(S)-Timolol maleate is , while it's Molecular Formula is C13H24N4O3S.C4H4O4. Anti hypertensive, Anti-glaucoma
The CAS number of (S)-Timolol maleate is 26921-17-5.
More information of (S)-Timolol maleate 26921-17-5 are:
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Synonyms |
Istalol;MK 950;Timololum [INN-Latin];Timacor;Timoptol;Optimol;(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol;2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (2S)-;Betime;Blocadren;Timoptic (TN);(2S)-1-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]-3-(tert-butylamino)propan-2-ol; |
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CAS Number |
26921-17-5 |
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Molecular Formula |
C13H24N4O3S.C4H4O4 |
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Molecular Weight |
432.498 |
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Melting Point |
202-203 °C(lit.) |
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Boiling Point |
487.2 °C at 760 mmHg |
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Flash Point |
248.5 °C |
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HS CODE |
29349990 |
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PSA |
182.58000 |
|
LogP |
0.67020 |
Timolol is a non-selective β-adrenergic receptor antagonist with log Kd values of -8.27, -9.86, and -6.8 for binding to human β1-, β2-, and β3-adrenoceptors, respectively. It has been reported that only the (S) enantiomer contributes to the β-blocking effects of racemic timolol, but the weakly active (R) isomer maintains a beneficial effect on intraocular pressure without the undesirable side-effect of bronchial constriction caused by non-selective action of (S)-timolol on β1 and β2 receptors. Timolol has been use alone and in fixed combinations with either prostaglandin analogs or carbonic anhydrase inhibitors to reduce intraocular pressure in research models of ocular hypertension and glaucoma.
InChI:InChI=1/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t10-;/m1./s1
Articles related to (S)-Timolol maleate:
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Article |
Source |
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Substituted aromatic amino-alcohol compound, and preparation method and application thereof |
- Paragraph 0127-0131, (2019/01/05) |
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Novel methods and compounds employed therein |
- , (2008/06/13) |
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