Your Location：Home >Products >small-molecule inhibitor >733750-99-7

733750-99-7

  • Product Name:AR 231453
  • Molecular Formula:C21H24FN7O5S
  • Molecular Weight:505.53
Inquiry

Product Details

pd_meltingpoint:174-176℃

Purity:99%

Manufacturer supply good quality AR 231453 733750-99-7 with stock

  • Molecular Formula:C21H24FN7O5S
  • Molecular Weight:505.53
  • Melting Point:174-176℃ 
  • Boiling Point:703.9±70.0 °C(Predicted) 
  • PKA:3.24±0.10(Predicted) 
  • PSA：168.31000 
  • Density:1.421±0.06 g/cm3(Predicted) 
  • LogP:5.30340 

733750-99-7 Relevant articles

Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119

Semple, Graeme,Fioravanti, Beatriz,Pereira, Guillherme,Calderon, Imelda,Uy, Jane,Choi, Karoline,Xiong, Yifeng,Ren, Albert,Morgan, Michael,Dave, Vibha,Thomsen, William,Unett, David J.,Xing, Charles,Bossie, Stuart,Carroll, Chris,Chu, Zhi-Liang,Grottick, Andrew J.,Hauser, Erin K.,Leonard, James,Jones, Robert M.

supporting information; experimental part, p. 5172 - 5175 (2009/07/01)

GPR119 is a rhodopsin-like GPCR expresse...

1,2,3-TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PRPPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO SUCH AS DIABETES AND HYPERGLYCEMIA

-

Page 195-196, (2010/02/07)

The present invention relates to certain...

733750-99-7 Process route

2-fluoro-4-methanesulfonylaniline
832755-13-2

2-fluoro-4-methanesulfonylaniline

5-(1-(6-chloro-5-nitropyrimidin-4-yl)piperidin-4-yl)-3-isopropyl-1,2,4-oxadiazole
1054579-82-6

5-(1-(6-chloro-5-nitropyrimidin-4-yl)piperidin-4-yl)-3-isopropyl-1,2,4-oxadiazole

(2-fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitro-pyrimidin-4-yl}-amine
733750-99-7

(2-fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitro-pyrimidin-4-yl}-amine

Conditions
Conditions Yield
With potassium carbonate; In 1,4-dioxane; at 250 ℃; for 0.0833333h; Microwave irradiation;
38%
(2-fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitro-pyrimidin-4-yl}-amine
733750-99-7

(2-fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitro-pyrimidin-4-yl}-amine

Conditions
Conditions Yield
38%

733750-99-7 Upstream products

  • 832755-13-2
    832755-13-2

    2-fluoro-4-methanesulfonylaniline

  • 1054579-82-6
    1054579-82-6

    5-(1-(6-chloro-5-nitropyrimidin-4-yl)piperidin-4-yl)-3-isopropyl-1,2,4-oxadiazole

Relevant Products

  • Friend Links:
  • Tel: +86-0533-2185556 Fax: +86-0533-2185556Email: admin@hangyubiotech.com
  • Address: Room 2516, Dingcheng Building, Beijing Road, Zhangdian District, Zibo City, Shandong Province
Copyright @2009-2025 Zibo Hangyu Biotechnology Development Co., Ltd