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501692-44-0

  • Product Name:Odevixibat
  • Molecular Weight:740.942
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Product Details

Purity:99%

Reputable factory supply Odevixibat 501692-44-0 in bulk at low price

  • Molecular Formula:C37H48N4O8S2
  • Molecular Weight:740.942
  • Density:1.34±0.1 g/cm3(Predicted) 

501692-44-0 Relevant articles

BENZOTHIAZEPINE AND BENZOTHIADIAZEPINE DERIVATIVES WITH ILEAL BILE ACID TRANSPORT (IBAT) INHIBITORY ACTIVITY FOR THE TREATMENT HYPERLIPIDAEMIA

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The present invention relates to compoun...

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501692-44-0 Process route

C<sub>41</sub>H<sub>56</sub>N<sub>4</sub>O<sub>8</sub>S<sub>2</sub>

C41H56N4O8S2

1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl})carbamoylmethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine
501692-44-0

1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl})carbamoylmethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine

Conditions
Conditions Yield
With trifluoroacetic acid; In dichloromethane; at 18 - 25 ℃; for 7h; Inert atmosphere;
0.056 g
1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-carboxymethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine
501692-63-3

1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-carboxymethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine

1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl})carbamoylmethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine
501692-44-0

1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl})carbamoylmethoxy-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1.1: 2,6-dimethylpyridine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 5 h / 18 - 25 °C / Inert atmosphere
2.1: trifluoroacetic acid / dichloromethane / 4.5 h / 18 - 25 °C / Inert atmosphere
3.1: 4-methyl-morpholine / N,N-dimethyl-formamide / 0.17 h / 18 - 25 °C / Inert atmosphere
3.2: 1 h / 18 - 25 °C / Inert atmosphere
4.1: trifluoroacetic acid / dichloromethane / 7 h / 18 - 25 °C / Inert atmosphere
With 4-methyl-morpholine; 2,6-dimethylpyridine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

501692-44-0 Upstream products

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  • 618908-39-7
    618908-39-7

    C37H49N3O7S2

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