Your Location:Home >Products >Supplement >1146963-51-0

1146963-51-0

  • Product Name:J-147
  • Molecular Formula:C18H17F3N2O2
  • Molecular Weight:350.3349896
Inquiry

Product Details

Purity:99%

Quality products make an important contribution to long-term revenue and profitability. Top quality factory supply 1146963-51-0 J-147 at low price

1.What is the J 147 ?

J 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer''s disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer''s disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide
1146963-51-0

2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: sodium acetate / ethanol; water / 0.33 h / 100 °C
2: triethylamine / dichloromethane / 0 °C / Inert atmosphere
With sodium acetate; triethylamine; In ethanol; dichloromethane; water;
1-(2,4-dimethylphenyl)-2-(3-methoxybenzylidene)hydrazine
391646-35-8

1-(2,4-dimethylphenyl)-2-(3-methoxybenzylidene)hydrazine

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide
1146963-51-0

2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

Conditions
Conditions Yield
With triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;
83%

2.What is the CAS number for J 147 ?

The CAS number of J 147 is 1146963-51-0.

More information of J 147 1146963-51-0 are:

CAS Number

1146963-51-0

Density

1.18±0.1 g/cm3(Predicted)

Boiling Point

412.8±55.0 °C(Predicted)

PSA

41.90000

LogP

4.24140

Pka

0.80±0.50(Predicted)

3.What are another words for J 147 ?

Synonyms for J 147 1146963-51-0:J 147;J147/J-147;2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide;J 147 2,2,2-Trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide

4.What is the molecular formula of J 147?

The chemical formula of  J 147 is C18H17F3N2O2 which containing 18 Carbon atoms,17 Hydrogen atoms,3 Fluorine atoms,2 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of  J 147 is 350.3349896.

5.What is J 147 (1146963-51-0) used for?

J 147 is a novel neurotrophic drug that serves as a cognitive enhancer and a therapeutic agent for Alzheimer's disease. It is an exceptionally potent, orally active, and broadly neuroprotective compound that has demonstrated the ability to enhance memory in normal animals and prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J 147 are linked to an increase in brain-derived neurotrophic factor (BDNF) levels, the expression of BDNF-responsive proteins, the enhancement of long-term potentiation (LTP), the preservation of synaptic proteins, and the reduction of amyloid plaques.

Relevant articles related to J 147:

Article

Source

6.Buy J 147 with the best price .

Zibo Hangyu Biotechnology Development Co., Ltd is a quality supplier of J 147. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on J 147 1146963-51-0.

Relevant Products