Your Location：Home >Products >Inhibitor >529488-28-6

529488-28-6

  • Product Name:Genz644282
  • Molecular Formula:C22H21N3O5
  • Molecular Weight:407.42
Inquiry

Product Details

pd_meltingpoint:254-257℃ (Decomposition)

Purity:99%

Manufacturer supply Genz644282 529488-28-6 with sufficient stock and high standard

  • Molecular Formula:C22H21N3O5
  • Molecular Weight:407.42
  • Melting Point:254-257℃ (Decomposition) 
  • Boiling Point:665.5±55.0 °C(Predicted) 
  • PKA:9.59±0.10(Predicted) 
  • PSA：83.84000 
  • Density:1.344±0.06 g/cm3(Predicted) 
  • LogP:3.05910 

529488-28-6 Relevant articles

5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Variation of N-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance

Ruchelman, Alexander L.,Houghton, Peter J.,Zhou, Nai,Liu, Angela,Liu, Leroy F.,LaVoie, Edmond J.

, p. 792 - 804 (2007/10/03)

5H-8,9-Dimethoxy-5-(2-N,N-dimethylaminoe...

529488-28-6 Process route

12-[2-(benzyl-methyl-amino)-ethyl]-2,3-dimethoxy-12<i>H</i>-8,10-dioxa-6,12-diaza-cyclopenta[<i>b</i>]chrysen-13-one
847573-86-8

12-[2-(benzyl-methyl-amino)-ethyl]-2,3-dimethoxy-12H-8,10-dioxa-6,12-diaza-cyclopenta[b]chrysen-13-one

2,3-dimethoxy-12-(2-(methylamino)ethyl)[1,3]dioxolo[4',5':4,5]-benzo[1,2-h]benzo[c][1,6]naphthyridin-13(12H)-one
529488-28-6

2,3-dimethoxy-12-(2-(methylamino)ethyl)[1,3]dioxolo[4',5':4,5]-benzo[1,2-h]benzo[c][1,6]naphthyridin-13(12H)-one

Conditions
Conditions Yield
With formic acid; acetic acid; palladium; at 20 ℃; for 1.5h;
95%
2-iodo-4,5-dimethoxybenzoic acid
61203-48-3

2-iodo-4,5-dimethoxybenzoic acid

2,3-dimethoxy-12-(2-(methylamino)ethyl)[1,3]dioxolo[4',5':4,5]-benzo[1,2-h]benzo[c][1,6]naphthyridin-13(12H)-one
529488-28-6

2,3-dimethoxy-12-(2-(methylamino)ethyl)[1,3]dioxolo[4',5':4,5]-benzo[1,2-h]benzo[c][1,6]naphthyridin-13(12H)-one

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1: oxalyl chloride / CH2Cl2 / 4 h / Heating
2: 1.44 g / Et3N / CH2Cl2 / 16 h / Heating
3: 35 percent / Pd(OAc)2; P(o-tolyl)3; Ag2CO3 / dimethylformamide / 0.5 h / Heating
4: 95 percent / formic acid; AcOH / Pd black / 1.5 h / 20 °C
With palladium diacetate; formic acid; oxalyl dichloride; acetic acid; triethylamine; tris-(o-tolyl)phosphine; silver carbonate; palladium; In dichloromethane; N,N-dimethyl-formamide;

529488-28-6 Upstream products

  • 847573-86-8
    847573-86-8

    12-[2-(benzyl-methyl-amino)-ethyl]-2,3-dimethoxy-12H-8,10-dioxa-6,12-diaza-cyclopenta[b]chrysen-13-one

  • 61203-48-3
    61203-48-3

    2-iodo-4,5-dimethoxybenzoic acid

  • 28657-75-2
    28657-75-2

    2-amino-4,5-methylenedioxy-acetophenone

  • 113258-92-7
    113258-92-7

    4,5-dimethoxy-2-iodobenzoyl chloride

Relevant Products

  • Friend Links:
  • Tel: +86-0533-2185556 Fax: +86-0533-2185556Email: admin@hangyubiotech.com
  • Address: Room 2516, Dingcheng Building, Beijing Road, Zhangdian District, Zibo City, Shandong Province
Copyright @2009-2026 Zibo Hangyu Biotechnology Development Co., Ltd