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1446711-81-4

  • Product Name:Alclometasone
  • Molecular Weight:292.31
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Product Details

Purity:99%

Cost-effective and customizable Alclometasone 1446711-81-4 factory

  • Molecular Formula:C15H17FN2O3
  • Molecular Weight:292.31

1446711-81-4 Relevant articles

PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF

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Paragraph 0181; 0184, (2018/09/12)

Provided herein are improved processes f...

Compounds and Compositions That Bind and Stabilize Transthyretin and Their Use for Inhibiting Transthyretin Amyloidosis and Protein-Protein Interactions

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Paragraph 0253; 0256, (2014/07/08)

Disclosed herein are compounds and compo...

1446711-81-4 Process route

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid methyl ester
1446701-54-7

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid methyl ester

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid
1446711-81-4

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid

Conditions
Conditions Yield
With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 14h; Inert atmosphere;
71%
With water; sodium hydroxide; In methanol; at 10 - 25 ℃; for 18h; Reagent/catalyst;
3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid hydrochloride

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid hydrochloride

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid
1446711-81-4

3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid

Conditions
Conditions Yield
With sodium hydrogencarbonate; In water; at 10 ℃; for 0.5h; pH=6 - 7;
83.2%

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    methyl 3-(3-bromopropoxy)-4-fluorobenzoate

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    3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)-propoxy]-4-fluoro-benzoic acid methyl ester

  • 214822-96-5
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    4-Fluoro-3-hydroxy-benzoic acid methyl ester

  • 1446701-53-6
    1446701-53-6

    C16H19FO5

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